DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4aa1 and CYP96A3

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_176713.1	Gene:	CYP96A3 / 842842	AraportID:	AT1G65340	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	113/560 - (20%)
Similarity:	214/560 - (38%)	Gaps:	137/560 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SILILLVISLSIYTFYATLNTYLRSVLLSLR-----LTGPPSLPFLGNCMLVTDKDLMRRCAGKA 76
            :|:|.|:...:.:.|:    .:.:.:||..:     ||..|:|..|...:|...         :.
plant     2 AIVIGLLEIFTAFVFF----IFFQCLLLHKKTPKPLLTNWPALGMLPGLLLQVP---------RI 53

  Fly    77 FDLYGSLVRIWVLLFPF----------FAVLEPEDLQVILSSK-KHTNKVFFYRLMHNFLGDGLI 130
            :|....::....:.|.|          ...::|.::..||||. .:..|...::.:...:||.:.
plant    54 YDWITEVLEATDMTFCFKGPCLSGMDILLTVDPVNIHYILSSNFANYPKGMEFKKIFEVVGDSIF 118

  Fly   131 TSSGSKWSNHRR-----------------------------LIQPAFHHNLLEKFIDTF----VD 162
            ......|.:.|.                             :::.|...|:|....|.|    .|
plant   119 NVDSGLWEDMRNSSHAIFSNQDFQMFWVSTSVRKLRQGLVPILENAADKNILVDLQDLFQRFLFD 183

  Fly   163 ASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPA 227
            .|..|....|.:.:..|:...::         .:||.||            .|..|        .
plant   184 TSLILMTGYDPKCLSVEMPKVEF---------GDAVDGV------------SDGVF--------Y 219

  Fly   228 RFTQPWLLLDGIYHWTKMANDELNQKKRL-------NDFTRKMIQRRRQIQNNNNG-----NSER 280
            |..:|      ::.|.......:..:|||       :....|:|..:|: :.|::|     ..|.
plant   220 RHVKP------VFLWRLQYLIGVGVEKRLKRGLAVFDQLLEKIITAKRE-EINSHGTHHPSRGEA 277

  Fly   281 KCLLDHMIEISESNRDFTEED----IVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLE 341
            ..:|.:.:.:..:...:.|..    |.:....|::|.:|:..:|:.:..:|:::|||..::...|
plant   278 IDVLTYYMTMDTTKYKYLEPSDDRFIKDTILGFLIAARDTTSSALTWFFWLMSKNPEAINKIRQE 342

  Fly   342 LATIFEDSNRAPTM--TDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNV-- 402
            :      :.:.|..  .||.::.|:...:.|.|||||.||     ...:.......||:|..|
plant   343 V------NKKMPRFDPADLEKLVYLHGAVCETLRLYPPVP-----FNHKSPAKPDVLPSGHRVDE 396

  Fly   403 ----FICPYATHRLAHIY-PDPEKFQPERFSPENSENRH--PYAFLPFSAGPRYCIGNRFAIMEI 460
                .|..||..|:..:: .|.|.|:|||:..::...:|  .|.||.|:||||.|:|.:...:::
plant   397 KWKIVISMYALGRMKSVWGDDAEDFRPERWISDSGRLKHEPSYKFLAFNAGPRACLGKKLTFLQM 461

  Fly   461 KTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRL 500
            ||:.:.::|:|.:..|.|..|.... .:..|...||.|.:
plant   462 KTVAAEIIRNYDIKVVEGHKTEPVP-SVLFRMQHGLKVNI 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	98/495 (20%)
CYP96A3	NP_176713.1	p450	22..502	CDD:386267	109/536 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010