DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	135/548 - (24%)
Similarity:	223/548 - (40%)	Gaps:	108/548 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGN---CMLVTDKDLMRRC-- 72
            :.|...:.||...:||:..:.|..:.......|..:.|  |.|.|.|   ..|....:.:.||
plant     1 MALLIFIFLLCFPISIFFIFFTKKSSSEFGFKSYPIVG--SFPGLVNNRHRFLDWTVETLSRCPT 63

  Fly    73 -------AGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVF-----FYRLMHNFL 125
                   .||.               .......|.:::.:|.:|..:   |     |..::.:||
plant    64 QTAIFRRPGKQ---------------QLIMTANPSNVEYMLKTKFES---FPKGQQFTSVLEDFL 110

  Fly   126 GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFI--DTFVDASQSLYENL-DAEAVGTEINIAKYVN 187
            |.|:..|.|..|...|:.....|....|..|:  :..|:.:..|...| :|...|..|::...:.
plant   111 GHGIFNSDGDMWWKQRKTASYEFSTKSLRDFVMSNVTVEINTRLVPVLVEAATTGKLIDLQDILE 175

  Fly   188 NCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQ 252
            ....|.:.:....|.....|.|.|:        |...|.|..|...::..   .:..:|:.....
plant   176 RFAFDNICKLAFNVDCACLGHDGAV--------GVNFMRAFETAATIISQ---RFRSVASCAWRI 229

  Fly   253 KKRLNDFTRKMIQ--------------RRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEEDIV 303
            ||:||..:.::::              |.|..|..::.:.|.  ||...|...|.|......|||
plant   230 KKKLNIGSERVLRESIATVHKFADEIVRNRIDQGRSSDHKED--LLSRFISKEEMNSPEILRDIV 292

  Fly   304 NEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPT---------MTDLH 359
               .:|:|||:|:..:|:::..:||:.:||.:|:.:.||.:|     ||.|         ...|.
plant   293 ---ISFILAGRDTTSSALSWFFWLLSMHPEVEDKILQELNSI-----RARTGKRIGEVYGFEHLK 349

  Fly   360 EMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGS----------NVFICPYATHRLAH 414
            .|.|:...|.|:|||||.||:..:...|:     :.||.|:          |:|    |..|:..
plant   350 MMNYLHAAITESLRLYPPVPVDIKSCAED-----NVLPDGTFVGKGWAITYNIF----AMGRMES 405

  Fly   415 IY-PDPEKFQPERFSPENS---ENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLP 475
            |: .|.::|.|||:..|.:   ....|..|..|.||||.|:|...|.:::|:||:.:|..: ::.
plant   406 IWGKDCDRFDPERWIDETNGCFRGEDPSKFPAFHAGPRMCVGKDMAYIQMKSIVAAVLERF-VVE 469

  Fly   476 VTGKTTIAATFRITLRASGGLWVRLKER 503
            |.||........:|||..|||:.|::||
plant   470 VPGKERPEILLSMTLRIKGGLFARVQER 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	116/481 (24%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	115/474 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920