DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP86C3

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_172773.4	Gene:	CYP86C3 / 837871	AraportID:	AT1G13140	Length:	534	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	134/568 - (23%)
Similarity:	231/568 - (40%)	Gaps:	118/568 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ERTTNLELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRC 72
            ||..| .||...:.|.: |.::.|........:.:       ||...|..|    :|.:....|
plant    12 ERVYN-HLCLSDVSLAL-LGLFVFCCVREKVTKKL-------GPTIWPVFG----ITPEFFFHR- 62

  Fly    73 AGKAFDLYGSLVR-------------IWVLLFPFFAV-LEPEDLQVILSS--KKHTNKVFFYRLM 121
                .|:||...|             || |...:.|| ..|.:::.:|.:  |......||....
plant    63 ----NDVYGWATRCLKKCRGTFLYNGIW-LGGSYGAVTCVPANVEYMLKTNFKNFPKGAFFKERF 122

  Fly   122 HNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSL---------------YENL 171
            ::.|.||:..:....|...||:|....|..   :|::.....:|.|               .|..
plant   123 NDLLEDGIFNADAESWKEQRRIIITEMHST---RFVEHSFQTTQDLVRKKLLKVMESFARSQEAF 184

  Fly   172 DAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDS----PFRQG----------K 222
            |.:.|...:.   :.|.|:..:             |.|...::..    ||.|.          :
plant   185 DLQDVLLRLT---FDNICIAGL-------------GDDPGTLDSDLPLVPFAQAFEEATESTMFR 233

  Fly   223 IMMPARFTQPWLLLD-GIYHWTKMANDELNQKKRLNDFTRKMIQRR--RQIQNNNNGNSERKCLL 284
            .|:|....:|....| |.....:.|.|.      :::|..||:..|  :..:....||  |..:|
plant   234 FMIPPFIWKPLKFFDIGYEKGLRKAVDV------VHEFVDKMVVDRICKLKEEGTLGN--RSDVL 290

  Fly   285 DHMIEISESNRDFTEED-----IVNEACT-FMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELA 343
            ..:||| ||::...|:|     ...:.|| |:|||:|:...|:.:..:::.::||.:::.:.|::
plant   291 SRIIEI-ESHKTTDEKDPSTIKFFRQFCTSFILAGRDTSSVALTWFFWVIQKHPEVENKIIREIS 354

  Fly   344 TIFEDSNRAP--------TMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHT-LPAG 399
            .|......:|        |:.:|::|.|::..:.|.:||||.:|:..::..|:......| :..|
plant   355 EILRQRGDSPTSKNESLFTVKELNDMVYLQAALSETMRLYPPIPMEMKQAIEDDVFPDGTFIRKG 419

  Fly   400 SNVFICPYATHRLAHIY-PDPEKFQPERF-SPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKT 462
            |.|:...||..|:..|: .|.|.|:|||: ...|..|...:.::.|:||||.|:|..||.:::||
plant   420 SRVYFATYAMGRMESIWGKDCESFKPERWIQSGNFVNDDQFKYVVFNAGPRLCLGKTFAYLQMKT 484

  Fly   463 IVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWV-----RLKERDH 505
            |.:.:|..|. :.|.....:......||....||.|     .|:|:.|
plant   485 IAASVLSRYS-IKVAKDHVVVPRVTTTLYMRHGLKVTISSKSLEEKIH 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	117/489 (24%)
CYP86C3	NP_172773.4	CYP86A	80..517	CDD:410687	110/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920