DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP86A1

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_200694.1	Gene:	CYP86A1 / 836003	AraportID:	AT5G58860	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	129/526 - (24%)
Similarity:	227/526 - (43%)	Gaps:	67/526 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VISLSIYT--FYATLNTYLRSVLLSLRLTGPPSLPFLGNC-MLVTDKDLMRRCAGKAFDLYGSLV 84
            |.:||:|.  ||          .||.|||||..|||:|:. .|:.::..:...........|...
plant    13 VAALSVYALWFY----------FLSRRLTGPKVLPFVGSLPYLIANRSRIHDWIADNLRATGGTY 67

  Fly    85 RIWVLLFPFFA--------VLEPEDLQVILSSK--KHTNKVFFYRLMHNFLGDGLITSSGSKWSN 139
            :...::.||.|        ...|::::.||.::  .:.....:....|:.||.|:..|.|..|..
plant    68 QTCTMVIPFVAKAQGFYTVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLM 132

  Fly   140 HRRLIQPAFHHNLLEKFIDTFVDAS--QSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVP 202
            .|:.....|....|.:.:..:|:.:  ..|:..||.   ..:.|....:.:..|.:..:.:.|:.
plant   133 QRKTAALEFTTRTLRQAMARWVNGTIKNRLWLILDR---AVQNNKPVDLQDLFLRLTFDNICGLT 194

  Fly   203 IKKRGQDVAM-MEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKM------ANDELNQKKRL---N 257
            ..|..:.::: :.|:||... .......|...||..| :.|...      :.|:|  ||.|   .
plant   195 FGKDPETLSLDLPDNPFSVA-FDTATEATLKRLLYTG-FLWRIQKAMGIGSEDKL--KKSLEVVE 255

  Fly   258 DFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEEDIVNE-ACTFMLAGQDSVGAAV 321
            .:....|..|:        ||....||...::..:.|.:....|::.. |..|:|||:|:...|:
plant   256 TYMNDAIDARK--------NSPSDDLLSRFLKKRDVNGNVLPTDVLQRIALNFVLAGRDTSSVAL 312

  Fly   322 AFTLFLLTQNPECQDRCVLELATIFEDS--NRAPTMT-------DLHEMRYMEMCIKEALRLYPS 377
            ::..:|:..|.|.:.:.|.||:.:.:::  |.....|       :...:.|::..:.|.||||||
plant   313 SWFFWLVMNNREVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVYLKAALAETLRLYPS 377

  Fly   378 VPLIARKLGEEVRLAKHT-LPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPENSEN----RH 436
            ||...:.:.::..|...| :|.||.|....|:..|:..|: .|..:|:|||:...:.|.    :.
plant   378 VPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKD 442

  Fly   437 PYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLK 501
            .|.|:.|:||||.|:|...|..::|::.|.:|..|::.||.|. .:.....:||....||.|.|:
plant   443 GYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGH-RVEQKMSLTLFMKNGLRVYLQ 506

  Fly   502 ERDHPL 507
            .|...|
plant   507 PRGEVL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	107/463 (23%)
CYP86A1	NP_200694.1	CYP86A	70..501	CDD:410687	104/446 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920