DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP735A1

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_198661.1	Gene:	CYP735A1 / 833833	AraportID:	AT5G38450	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	142/548 - (25%)
Similarity:	244/548 - (44%)	Gaps:	88/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LCSILILLVISLSIYTFYATLNTY------LRSVLLSLRLTGPPSLPFLGNCMLVT---DKDLMR 70
            |.|:|::.|.:: :...|.|::.|      ::.::....:|||...|..||.:.::   .:...:
plant     6 LKSLLVIFVTTI-LRVLYDTISCYWLTPRRIKKIMEQQGVTGPKPRPLTGNILEISAMVSQSASK 69

  Fly    71 RCAGKAFDL--------------YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLM 121
            .|.....|:              ||....:|....|...:.|.|.::.:|  .|| |.|.....:
plant    70 DCDSIHHDIVGRLLPHYVAWSKQYGKRFIVWNGTDPRLCLTETELIKELL--MKH-NGVSGRSWL 131

  Fly   122 H-----NFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVG---T 178
            .     ||:|.||:.::|..|.:.|.|..|||....|:.:....|:.:..|.|.|..| ||   .
plant   132 QQQGTKNFIGRGLLMANGQDWHHQRHLAAPAFTGERLKGYARHMVECTSKLVERLRKE-VGEGAN 195

  Fly   179 EINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGK------IMMPARFTQP--WLL 235
            |:.|.:.::....||::....|               |.|.:||      .::..|..|.  .|.
plant   196 EVEIGEEMHKLTADIISRTKFG---------------SSFEKGKELFNHLTVLQRRCAQATRHLC 245

  Fly   236 LDGIYHWTKMANDELNQ-KKRLNDFTRKMIQRRRQI----QNNNNGNSERKCLLDHM-IEISESN 294
            ..|........|.|:.. ||.:.....::||.||..    :::.:|:.....||:.| |:.:.:|
plant   246 FPGSRFLPSKYNREIKSLKKEVERLLIEIIQSRRDCAEMGRSSTHGDDLLGLLLNEMDIDKNNNN 310

  Fly   295 RDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLH 359
            .:...:.|::|..||..||.::....:.:|..||..||..|::...|:..:| ..|..|::..|.
plant   311 NNNNLQLIMDECKTFFFAGHETTALLLTWTTMLLADNPTWQEKVREEVREVF-GRNGLPSVDQLS 374

  Fly   360 EMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQ 423
            ::..:...|.|:|||||...|:.|...|:::|...|:|.|.:::|...|.|....:: .|..:|.
plant   375 KLTSLSKVINESLRLYPPATLLPRMAFEDLKLGDLTIPKGLSIWIPVLAIHHSEELWGKDANQFN 439

  Fly   424 PERFSPEN-SENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFR 487
            ||||.... :..||   |:||:||||.|||.:||:||.|.|::.|:..:..       ||:..:|
plant   440 PERFGGRPFASGRH---FIPFAAGPRNCIGQQFALMEAKIILATLISKFNF-------TISKNYR 494

  Fly   488 ------ITLRASGGLWVRLKERDHPLIA 509
                  :|::...|:.|.||    ||::
plant   495 HAPIVVLTIKPKYGVQVILK----PLVS 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	124/465 (27%)
CYP735A1	NP_198661.1	PLN02290	1..518	CDD:215164	142/546 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910