DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP96A13

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_195910.1	Gene:	CYP96A13 / 831752	AraportID:	AT5G02900	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	126/540 - (23%)
Similarity:	220/540 - (40%)	Gaps:	123/540 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYGSLVR 85
            |...|::|:.|          ::|...|...|.|..|...:|...         :.:|....::.
plant     6 LFEASIAIFCF----------IILHFFLGNWPVLGMLPGLLLEFH---------RIYDFSVEVLE 51

  Fly    86 IWVLLFPF-----------FAVLEPEDLQVILSS--KKHTNKVFFYRLMHNFLGDGLITSSGSK- 136
            ...|.|||           |.| :|.::..|:||  ..:|....|.::...| |||::|:..|:
plant    52 NSDLTFPFKGPWFTGMDMLFTV-DPTNIHHIMSSNFSNYTKGPDFKQVFDVF-GDGILTTDDSEL 114

  Fly   137 WSNHRRLIQPAFHHNLLEKFIDTFVDA----SQSLYENLDAEAVGT-----------EINIAKYV 186
            |.|.::......:|...:| ..|.||.    .:.:::.......|:           |:..||
plant   115 WKNLKKASLVMLNHQGFQK-NGTVVDLQDVFKRFMFDTTLVTVTGSADPRSLSIEMPEVEFAK-- 176

  Fly   187 NNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELN 251
               .||.:.|.::                           .|..:|.||      |.........
plant   177 ---ALDHVGEGIM---------------------------HRHVRPRLL------WKLQKCVGFG 205

  Fly   252 QKKR-------LNDFTRKMIQRRRQ------IQNNNNGNSERKCLLDHMIEISESNRDFTEEDIV 303
            |:|:       ||....|.|..:|:      ...::|| ||.:.:|.:.|:|     |.|:.:::
plant   206 QEKKFSKADATLNQACAKYILEKREETRSQGFDYHSNG-SESEDILTYHIKI-----DTTKYELL 264

  Fly   304 NEA---------CTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATI--FEDSNRAPTMTD 357
            |.:         ..|:|||:|:..:|:.:..:||.:||:...:...|:.|.  .::......|..
plant   265 NPSDDKFLRDTILAFVLAGRDTTASALTWFFWLLLENPQVVTKIRQEINTSNGGQEKPSCEPMEY 329

  Fly   358 LHEMRYMEMCIKEALRLYPSVPLIARK-LGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPE 420
            |:.:.|:...:.||:||||.||..... :..:|..:.|.:.:...:.|..||..|:..:: .|..
plant   330 LNNLVYLHGALYEAMRLYPPVPFERMSPIKPDVLPSGHKVDSSMKILIFIYALGRMRAVWGEDAS 394

  Fly   421 KFQPERFSPENSENRH--PYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIA 483
            :|:|||:..|.:..||  .:.||.|:||||.|||.:.|:..:|.:|..:|::|.:..|.|:..|.
plant   395 EFKPERWLSETTSLRHEPSFKFLAFNAGPRSCIGKQLAMTLMKIVVVEILQNYDIKVVKGQKKIE 459

  Fly   484 ATFRITLRASGGLWVRLKER 503
            ......||...||.|.|.::
plant   460 PAPGPILRMKHGLRVTLTKK 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	111/481 (23%)
CYP96A13	NP_195910.1	p450	1..479	CDD:299894	126/538 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010