DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	124/544 - (22%)
Similarity:	236/544 - (43%)	Gaps:	82/544 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LELCSILILLVISLSIYTFYATLN------TYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRR 71
            :.:.|:.:.:.:.:..:..:.||.      ..|.|.|....|.|.|..|.:|:  |..:..:...
plant     3 ISVASVTVSVAVVVVSWWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGD--LKKNFSMRAE 65

  Fly    72 CAGKAFDL------------------YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFY 118
            ...|..:|                  :|.....|....|...:::||.:..:|      |||:.:
plant    66 ARSKPINLTDDITPRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVL------NKVYDF 124

  Fly   119 RLMHNF-----LGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSL---YENL--DA 173
            :..|.|     :..|:::..|.||:.|||:|.||||...::..:..|..:...:   ::.|  |.
plant   125 QKAHTFPLGRLIATGVLSYDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDK 189

  Fly   174 EAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDG 238
            |: ..|:::...:.:...|:::....|....: ||.:..:      |.::......|.....:.|
plant   190 ES-SCEVDVWPGLVSMTADVISRTAFGSSCVE-GQRIFEL------QAELAQLIIQTVRKAFIPG 246

  Fly   239 IYHWTKMANDELNQKKR-LNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTE--- 299
            ..:.....|..:..|.| :....|.::.:|  ::....|.:....||..::   |||...|:
plant   247 YSYLPTKGNRRMKAKAREIQVILRGIVNKR--LRAREAGEAPNDDLLGILL---ESNLGQTKGNG 306

  Fly   300 ---EDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEM 361
               ||::.|...|...||::....:.:|:.||:|:.:.|.|...|:..:|.|  :.|....|:::
plant   307 MSTEDLMEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGD--KEPDAEGLNQL 369

  Fly   362 RYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPE 425
            :.|.|.:.|.|||||.:|.::|.:.:|:.|...|||.|..:.:......|...:: .|..:|:|:
plant   370 KVMTMILYEVLRLYPPIPQLSRAIHKEMELGDLTLPGGVLINLPILLVQRDTELWGNDAGEFKPD 434

  Fly   426 RFSPENSE-NRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLR--SYQLLPVTGKTTIAATFR 487
            ||....|: .::..:|.||:.|.|.|||..||::|.|..::.:|:  |::|.|    :.:.|.:.
plant   435 RFKDGLSKATKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRFSFELSP----SYVHAPYT 495

  Fly   488 I-TLRASGGLWVRLKERDHPLIAH 510
            : |:....|.         |||.|
plant   496 VFTIHPQFGA---------PLIMH 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	109/463 (24%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	123/523 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810