Protein Alignment Cyp4aa1 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 503
• Identity: 151/503 - (30%)
• Similarity: 257/503 - (51%)
• Gaps: 35/503 - (6%)

  Fly    20 ILLVISLSIYTFYATLNTYLRSVLLSLRLT---GPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYG 81
            :.||..|::....| :..|||...|...|:   |||:...||:...:.:.::         :...
Mouse    16 LALVFCLALVLMQA-MKLYLRRQRLLRDLSPFPGPPAHWLLGHQKFLQEDNM---------ETLD 70

  Fly    82 SLVRIWVLLFP--------FFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWS 138
            .:|:.....||        ||.:.:|:..::.| |:......:.::|:...:|.||:...|.:|.
Mouse    71 EIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFL-SRTDPKMQYLHQLLTPCIGRGLLNLDGPRWF 134

  Fly   139 NHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDA--EAVGTEINIAKYVNNCVLDILNEAVLG- 200
            .||.|:.||||.::|:..:||...:.:.:.:..:.  ....|.|.:.:::|...|||:.:...|
Mouse   135 QHRCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQ 199

  Fly   201 -VPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMI 264
             ...:..|...:.:: :.|..|:| :.:|....|...|.|:..:...:......|.::.:|.|:|
Mouse   200 ETNCQINGTYESYVK-ATFELGEI-ISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEKII 262

  Fly   265 QRRRQIQNN---NNGNSERKCLLDHMIEI-SESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTL 325
            |.|::|..|   .:.....:..||.::.. :|..|.|::.|:..|..|||.||.|:..|::::.|
Mouse   263 QDRKKILKNQVKQDDTQTSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLL 327

  Fly   326 FLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVR 390
            :.|..|||.||||..|:.:|..|.: :.|...|.||.|..|||||.|||.|.||.|:|:|.:.:.
Mouse   328 YCLALNPEHQDRCRTEIRSILGDGS-SITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLT 391

  Fly   391 LAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNR 454
            |.. |:||||..|.:..:..|....::.||:.|.|.||:.|||:.|||.||||||:|||.|||.:
Mouse   392 LPDGHSLPAGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQ 456

  Fly   455 FAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKE 502
            ||::|:|..::.:|..:|:.|...:.. |.:....||...|:::.||:
Mouse   457 FAMLELKVAIALILLHFQVAPDLTRPP-AFSSHTVLRPKHGIYLHLKK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	135/433 (31%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	135/447 (30%)