Protein Alignment Cyp4aa1 and cyp11a1.1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_694485.2
• Gene: cyp11a1.1 / 80374
• ZFINID: ZDB-GENE-010306-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 437
• Identity: 101/437 - (23%)
• Similarity: 179/437 - (40%)
• Gaps: 75/437 - (17%)

  Fly    77 FDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSK-KHTNKV-----FFYRLMHNFLGDGLITSSGS 135
            |..:|.:.|..|.::....:::|||..::..:: .|.|::     ..||...| ...|::...|.
Zfish    75 FKTFGPIYREKVGIYDSVYIIKPEDGAILFKAEGHHPNRINVDAWTAYRDYRN-QKYGVLLKEGK 138

  Fly   136 KWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIA---KYVNNCVLDILNEA 197
            .|...|.::....   ||.|...|||...:.:.::..|. |..:|..:   ::..:...|:...:
Zfish   139 AWKTDRMILNKEL---LLPKLQGTFVPLLEEVGQDFVAR-VNKQIERSGQKQWTTDLTHDLFKFS 199

  Fly   198 VLGVPIKKRGQDVAMMEDS--PFRQG---------KIMMPARFTQPWLL--------------LD 237
            :..|.....|:.:.::.|:  |..|.         |...|..:..|.||              .|
Zfish   200 LESVSAVLYGERLGLLLDNIDPEFQHFIDCVSVMFKTTSPMLYLPPGLLRSIGSNIWKNHVEAWD 264

  Fly   238 GIYHWTKMANDELNQKKRL--NDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEE 300
            ||:          ||..|.  |.|        :|.:.|..||.:...:|..::    .....:.|
Zfish   265 GIF----------NQADRYIQNIF--------KQWKENPEGNGKYPGVLAILL----MQDKLSIE 307

  Fly   301 DIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYM- 364
            ||.......|..|.|||...:.:||:.|.:.|:.||....|::     :.|.....|:.:|..|
Zfish   308 DIKASVTELMAGGVDSVTFTLLWTLYELARQPDLQDELRAEIS-----AARIAFKGDMVQMVKMI 367

  Fly   365 ---EMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPER 426
               :..:||.|||:|....:.|.:.|:..:..:.:|||:.|.:..||..|....:|.||::.|.|
Zfish   368 PLLKAALKETLRLHPVAMSLPRFITEDTVIQNYHIPAGTLVQLGVYAMGRDHQFFPKPEQYCPSR 432

  Fly   427 FSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL 473
            :.   |..|..:..|.|..|||.|:|.|.|..|::..:..:|.::::
Zfish   433 WI---SSKRQYFKSLGFGFGPRQCLGRRIAETEMQIFLIHMLENFRI 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	100/433 (23%)
cyp11a1.1	NP_694485.2	cytochrome_P450	75..498	CDD:477761	101/437 (23%)