Protein Alignment Cyp4aa1 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 534
• Identity: 164/534 - (30%)
• Similarity: 258/534 - (48%)
• Gaps: 75/534 - (14%)

  Fly    19 LILLVISLSIYTFYATLNTYLRSVL-LSLRLTGPPSLP----FLGNCMLVTDKDLMRRCAGKAFD 78
            |:||:...|....|  :.|.:..|. .||||...|..|    .||:..|:...:       :...
Mouse    20 LLLLLAGASCLLAY--ILTPIYGVFENSLRLRCFPQPPKRNWILGHLGLIQSSE-------EGLL 75

  Fly    79 LYGSLVRI-------WV--------LLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDG 128
            ...||||.       ||        :..|.|  ::|..|...|.:.|.|   .|||.:..:||||
Mouse    76 YIQSLVRTFRDACCWWVGPLHPVIRIFHPAF--IKPVVLAPALVAPKDT---VFYRFLKPWLGDG 135

  Fly   129 LITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLD--AEAVGTEINIAKYVNNCVL 191
            |:.|:|.|||.|||::.||||.|:|:.::..|.|::..::....  |......:|:.::::...|
Mouse   136 LLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQRLASKGSAYLNMFEHISLMTL 200

  Fly   192 DILNEAVLGVPI----KKRGQDVAMMEDSPFRQGKIMMPARFTQPWLL-LDGIYHWTKMANDELN 251
            |.|.:.|.....    |......|::|.|       .:.||..|..|| :|..|:.|   :|.:.
Mouse   201 DSLQKCVFSFDSNCQEKPSEYITAILELS-------TLVARRHQRLLLHVDLFYYLT---HDGMR 255

  Fly   252 QKKR---LNDFTRKMIQRRRQIQNNNNGNSERKC-----LLDH----MIEISESNRDFTEEDIVN 304
            .:|.   ::|||..:|:.||:...:..|....|.     .||.    ::...|..:..::|||..
Mouse   256 FRKACRLVHDFTDAVIRERRRTLLDQGGVDVLKAKAKAKTLDFIDVLLLSKDEHGKALSDEDIRA 320

  Fly   305 EACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAP---TMTDLHEMRYMEM 366
            ||.|||..|.|:..:.:::.|:.|.::||.|:||..|:..:..|  |.|   ...||.::.::.|
Mouse   321 EADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRD--REPEEIEWDDLAQLPFLTM 383

  Fly   367 CIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPE 430
            ||||:|||:|.|..|:|...:::.|.. ..:|.|....|..:.||....::||||.:.|.||..:
Mouse   384 CIKESLRLHPPVTAISRCCTQDIVLPDGRVIPKGVISRISIFGTHHNPAVWPDPEVYDPFRFDAD 448

  Fly   431 NSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGG 495
            |.:.|.|.||:|||||||.|||..||:.|:|..::..|..:::||...:.....  .:.|||.||
Mouse   449 NVKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLPDDKEPRRKP--ELILRAEGG 511

  Fly   496 LWVRLKERDHPLIA 509
            ||::::    ||.|
Mouse   512 LWLKVE----PLSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	144/454 (32%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	145/459 (32%)