Protein Alignment Cyp4aa1 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001038763.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 491
• Species: Danio rerio
• Alignment Length: 524
• Identity: 133/524 - (25%)
• Similarity: 227/524 - (43%)
• Gaps: 90/524 - (17%)

  Fly    19 LILLVISL--SIYTFYATLNTYLRSVLLSL-RLTGPPSLPF-LGNCMLVTD--------KDLMRR 71
            |:.:|..|  :::..:.....|:..|.... .:.|||...| ||:...:..        .||:..
Zfish     6 LLYMVFYLLSAVFVVFLAYCLYIHQVHQKYDHIPGPPRDNFLLGHIPTINRVTKSERHMNDLLLI 70

  Fly    72 CAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLM-----HNFLGDGLIT 131
            .|.|    ||.:.|:....:....|..||..:.|:.|.|:....|.|:.:     ..|||.||:|
Zfish    71 WAEK----YGPVYRLNSFHYVIINVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGKRFLGYGLVT 131

  Fly   132 SSGSK-WSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCV-LDIL 194
            ::... |...||::.|||..:.|...|.||.:.|:.|.:.|:..|:.....:...:.||| |||:
Zfish   132 ATDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEMAINKTPAVMHDLVNCVTLDII 196

  Fly   195 NEAVLGVPIKKRGQDVAMMEDSPFRQG------KIMMPAR------FTQPWLLLD---GIYHWTK 244
            .:...||.:     ::....|:||:|.      .:::..|      |.:.|..:.   |.....:
Zfish   197 CKVAFGVDL-----NLFKQTDNPFQQAIEQCLQGMVLDLRDPFCKFFPKNWKAIQETKGATVLLR 256

  Fly   245 MANDELNQKKRL---------NDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEE 300
            ...::..|.::.         ||...::::..::.:.||..:.|:  :||:.:
Zfish   257 KTGEQWIQNRKTAVEIGEDVPNDILTQILKTAKEEKVNNTKDHEQ--MLDNFV------------ 307

  Fly   301 DIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYME 365
                   ||.:|||::....::|.:..|.::||...|...|:..:. .:.|..:..||.:..|:.
Zfish   308 -------TFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVL-GTKRDISYEDLGKFTYLS 364

  Fly   366 MCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPE 430
            ..:||.|||||:.|...|.|.|::.:....:|.|.:|....|...||...:.||.||.||||
Zfish   365 QVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKFDPERF--- 426

  Fly   431 NSENRHP-YAFLPFSAGPRYCIGNRFA-IMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITL--- 490
            |.....| |.:.|||.|||.|:|..|: ....:..:::||.  |||      |:.:.|.|.|
Zfish   427 NVNAPKPYYCYYPFSLGPRSCLGQVFSQATPAEGALAQLLT--QLL------TLCSHFLIVLYFS 483

  Fly   491 RASG 494
            ::||
Zfish   484 KSSG 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	121/466 (26%)
cyp46a1.3	NP_001038763.1	p450	39..452	CDD:278495	116/446 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820