Protein Alignment Cyp4aa1 and cyp46a1.5

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001417768.2
• Gene: cyp46a1.5 / 641477
• ZFINID: ZDB-GENE-051120-33
• Length: 501
• Species: Danio rerio
• Alignment Length: 526
• Identity: 150/526 - (28%)
• Similarity: 238/526 - (45%)
• Gaps: 78/526 - (14%)

  Fly    20 ILLVISLSIYTFYATLNTYLRSVLLSL-RLTGPPSLPF-LGNCMLVTDK---------DLMRRCA 73
            |:|.:..:::|.:.....|:..:.... .:.|||...| ||:...:|..         ||..:.|
Zfish     9 IILYLLAAVFTAFFAYCLYVHHIHQKYDHIPGPPRDNFLLGHSPSLTKALYSDDSLIYDLFLQWA 73

  Fly    74 GKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHN-----FLGDGLITS- 132
            .|    ||.:.||..|.:....|..||..:.|:.|.|:|...|.||.:.|     |||.||||:
Zfish    74 EK----YGPVYRINTLHYVTIVVYCPEATKTIMMSPKYTKDPFVYRRVFNLFGKRFLGYGLITAV 134

  Fly   133 SGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCV-LDILNE 196
            ....|...||::.|||..:.|...|.||.:.|:.|.:.|:..|......:...:.||| ||::.:
Zfish   135 DHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEIANNKTPAVMHDLVNCVTLDVICK 199

  Fly   197 AVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFT------------QPWLLLDGIYHWTKMANDE 249
            ...||.:     :....:||||:....:.....|            :.|.|:..:...|::
Zfish   200 VAFGVDL-----NFLTQKDSPFQNAVELCLKGMTFDVRDPLFRIIPKNWKLIQQVREATEL---- 255

  Fly   250 LNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISE-----SNRDFTEEDIVNEACTF 309
                  |.....|.||.|:...  .||....|.:|..:::.:|     |..||  |.:::...||
Zfish   256 ------LRKTGEKWIQNRKTAV--KNGEDVPKDILTQILKSAEEQNVTSTEDF--EQMLDNFVTF 310

  Fly   310 MLAGQDSVGAAVAFTLFLLTQNPECQDRCVLE----LATIFEDSNRAPTMTDLHEMRYMEMCIKE 370
            .:|||::....::|.:..|.:|||...|...|    |.|..|.||.     ||.::.|:...:||
Zfish   311 FMAGQETTANQLSFAIMELGRNPEIYKRAKAEVDEVLGTKREISNE-----DLGKLTYLSQVLKE 370

  Fly   371 ALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENR 435
            .|||||:.|...|.|.|::.:....:|.|.:|....:.:.||...:.||.||.|:||. ||:...
Zfish   371 TLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVMFNSFVSQRLEKFFKDPLKFDPKRFD-ENAPKP 434

  Fly   436 HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRI----TLRASGGL 496
            : |.:.||:.|||.|||..|:.||.|.::::||:.::...|.|:     :|.|    |||...|:
Zfish   435 Y-YTYYPFALGPRTCIGQVFSQMEAKVVLAKLLQRFEFSLVPGQ-----SFDIKDTGTLRPKSGV 493

  Fly   497 WVRLKE 502
            ...:|:
Zfish   494 ICYIKQ 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	133/448 (30%)
cyp46a1.5	NP_001417768.2	None