Protein Alignment Cyp4aa1 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 534
• Identity: 147/534 - (27%)
• Similarity: 247/534 - (46%)
• Gaps: 87/534 - (16%)

  Fly    19 LILLVISLS---------IYTFYATLNTYLRSVLLSLRLTGPPSLP----FLGNCMLVTDKDLMR 70
            |:..::.:|         :||.||...          ||.|.|..|    |.|:..:....:...
Mouse    47 LLFFLVGISWFLARFLTQLYTLYAKCQ----------RLCGFPQPPKKNWFWGHLGMSPPTEEGM 101

  Fly    71 RCAGKAFDLYGSLVRIWV-LLFPFFAVLEPEDLQVILSSKKHT--NKVFFYRLMHNFLGDGLITS 132
            :...:....|......|: .:.|...:..|:.::.:||:....  ....||..:..:|||||:.|
Mouse   102 KQVTELVTTYPQGFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDDIFYSFLKPWLGDGLLVS 166

  Fly   133 SGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVG--TEINIAKYVNNCVLDILN 195
            :|.||:.|||::.||||.|:|:.::..|.|::..::......|.|  |.:|:.:.::...||.|.
Mouse   167 AGDKWNRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWLRLASGGSTRLNMFENISLMTLDTLQ 231

  Fly   196 EAV--------------------LGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIY 240
            :.|                    |.....||.:.:.|..|..:|              |..||:.
Mouse   232 KCVFSFNSNCQEKPSQYIAAILELSTLAVKRNEQLLMHVDLLYR--------------LTPDGMR 282

  Fly   241 HWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKC-----LLDH----MIEISESNRD 296
            .:...        :.::|||..:||.||:....:.|:...|.     .||.    ::...|..::
Mouse   283 FYKAC--------RLVHDFTDAVIQERRRTLLKHGGDDIIKAKAKSKTLDFIDVLLLTKDEDGKE 339

  Fly   297 FTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAP---TMTDL 358
            .::|||..||.|||..|.|:..:.:::.|:.|.::||.|:||..|:..:..|  |.|   ...||
Mouse   340 LSDEDIRAEADTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELLRD--RDPKEIEWDDL 402

  Fly   359 HEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKF 422
            .::.::.|||||:|||:|.|.:::|...:::.|.. ..:|.|....|..:.||....::.|||.:
Mouse   403 AQLPFLTMCIKESLRLHPPVTMVSRCCTQDISLPDGRIIPKGVICIINIFGTHHNPTVWRDPEVY 467

  Fly   423 QPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFR 487
            .|.||.|||.:.|.|.:|:|||||||.|||..||:.|:|..::..|..:::||...:.....  .
Mouse   468 DPFRFDPENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRILPDDKEPRRKP--E 530

  Fly   488 ITLRASGGLWVRLK 501
            :.|||.||||:|::
Mouse   531 LILRAEGGLWLRVE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	131/454 (29%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	133/466 (29%)