Protein Alignment Cyp4aa1 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 536
• Identity: 138/536 - (25%)
• Similarity: 226/536 - (42%)
• Gaps: 111/536 - (20%)

  Fly    17 SILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMR---RCAGKAFD 78
            ::::|::..|.||      ..:.....:.|.:.||...||:|. :|...|.|..   .||.|
Zfish    12 TLVVLVITLLFIY------GVWPHRFFIKLGIPGPRPWPFVGT-LLSYAKGLCNFDMECAKK--- 66

  Fly    79 LYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLG---DGLITSSGSKWSNH 140
             ||.:..|:....|...|.:.|.::|:|..:.::|.:...:......|   ||:|.....:|...
Zfish    67 -YGKVWGIYDGRLPILMVADLEVIKVVLVKECYSNFINRRKRTTGLAGPFSDGIIMVKDERWKRM 130

  Fly   141 RRLIQPAFHHNLLEKFI-------DTFV-----------------------DASQSLYENLDAEA 175
            |..:.|.|....|::..       |.|:                       |...|...::|.::
Zfish   131 RSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKKDPEQPVKIKEVVAPYSLDVITSSSFSVDIDS 195

  Fly   176 VGTE-----INIAKYV-----NNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFT 230
            :...     ||:.|::     |..:|.||....|.:|:||.|  |.:...|
Zfish   196 INNPEDPFVINVKKFIQFNMFNPLLLLILLFPSLAIPLKKMG--VTLFSKS-------------- 244

  Fly   231 QPWLLLDGIYHWTKMANDELNQKKRLN-DFTRKMIQRR---RQIQNNNNGNSERKCLLDHMIEIS 291
                .:|..|...|...|:.|::.... ||.:.|:|.:   .|||:::......|.|.||
Zfish   245 ----AMDFFYSVLKKIKDDHNKESEGRVDFLKLMLQNQIPDDQIQDSDTSEQPAKGLTDH----- 300

  Fly   292 ESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSN---RAP 353
                     :|::::..|:|.|.::....:.|.|:.|..||:|.::.|.|:     |.|   ..|
Zfish   301 ---------EILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEI-----DKNFPLDTP 351

  Fly   354 TMTD-LHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYP 417
            ...| |..|.|:||.|.|::||.|:.|.:.|...:.|.:...|:|.|:.|.|..|.......|:.
Zfish   352 ITYDALMRMDYLEMAINESMRLLPTAPRLERSAKKTVVINGLTIPEGTLVGIPTYVLSHDPDIWE 416

  Fly   418 DPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL-------LP 475
            .|.:|:||||||||......|||:||..|||.|||.|:|:|.:|..|.:||:::.:       :|
Zfish   417 SPGEFRPERFSPENKSEFLQYAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIP 481

  Fly   476 VTGKTTIAATFRITLR 491
            :....|......|||:
Zfish   482 LEMNVTFQPKVPITLK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	121/469 (26%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	122/473 (26%)