Protein Alignment Cyp4aa1 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 529
• Identity: 109/529 - (20%)
• Similarity: 208/529 - (39%)
• Gaps: 101/529 - (19%)

  Fly    19 LILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDL---- 79
            ::||.:|..::.|..:: |..|:..|.|. .|....|.:|.    |...|.:   |.:|.:
Zfish    23 VLLLAVSRLLWEFRWSI-TRDRTCKLPLP-QGSMGWPLVGE----TFHWLFQ---GSSFHISRRE 78

  Fly    80 -YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLG-DGLITSSGSKWSNHRR 142
             :|.:.:..:|..|...|...|:::.||..:.......:.:.....|| :.|:.|.|......|:
Zfish    79 KHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQWPQSTRIILGPNTLVNSVGDLHKRKRK 143

  Fly   143 LIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRG 207
            ::...|....||.::....|..:|.......|....|:..|  ..:....|....:||:.:::
Zfish   144 VLAKVFSRGALEAYLTRLQDVVKSEIAKWCTETGSVEVYTA--AKSLTFRIAVRVLLGLHLEE-- 204

  Fly   208 QDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMA--NDELNQKKRLNDFTRKMIQRRRQI 270
            |.:..:..: |.|   :|...|:.|   :|     |.::  ...:..::.|:....|:|:.:.:.
Zfish   205 QQITYLSKT-FEQ---LMNNLFSLP---ID-----TPVSGLRKGIRAREILHSAMEKIIEEKLKK 257

  Fly   271 QNNNNGNSERKC-LLDHMIEIS-ESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPE 333
            |..::     .| ..|:|:..: |::.:.|.:::...|...:.|...:..:|....:..|.::|:
Zfish   258 QQASD-----YCDAFDYMLSSARENDYELTMQELKETAVELIFAAHSTTASASTSLIMQLLRHPD 317

  Fly   334 ---------------------CQDRC---------------------VLELATIF-----EDSNR 351
                                 |:.||                     .:..||.|     |:..|
Zfish   318 VSERARAELESEGLITDGHGHCRSRCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRR 382

  Fly   352 APT------MTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATH 410
            :.|      :..|.::.|::..:||.||..|.|....|.:.:...|..:.:|.|.:|......||
Zfish   383 SRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTFELNGYQIPKGWSVMYSIRDTH 447

  Fly   411 RLAHIYPDPEKFQPERFSPENSENR-HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLL 474
            ..|..|.:||.|.|:||.....|:: ..::::||..|.|.|||...|::.:||:...||
Zfish   448 ETAEAYQNPELFDPDRFCVGREESKSERFSYVPFGGGVRRCIGRELALIVLKTLAVELL------ 506

  Fly   475 PVTGKTTIA 483
             .|...|:|
Zfish   507 -ATADCTLA 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	94/462 (20%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	99/491 (20%)