Protein Alignment Cyp4aa1 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 509
• Identity: 122/509 - (23%)
• Similarity: 211/509 - (41%)
• Gaps: 92/509 - (18%)

  Fly    14 ELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCML------VTDKDLMRRC 72
            |..::|..||..|.||..:.  :.|.:    .|.:.||.::||.|..:.      |.|.|
Zfish     6 ETWTLLAFLVALLVIYGSWP--HRYFK----KLGIPGPKTIPFFGTMLRYKDGFHVFDMD----- 59

  Fly    73 AGKAFDLYGSLVRIWVLL---FPFFAVLEPEDLQVILSSKKH---TNKVFFYRLMHNFLGDGLIT 131
               .|:.||   |||.:.   .|...:::...::.:|..:.:   ||:..|  .::..|.|.:..
Zfish    60 ---CFEKYG---RIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNF--RLNGALYDAVSI 116

  Fly   132 SSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAV-GTEINIAKYVNNCVLDILN 195
            :....|...|.::.|:|....|::........|..|.:::...|. |...:|.::.....:|::.
Zfish   117 AEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVT 181

  Fly   196 EAVLGVPIKKRGQDVAMMEDSPFRQG-KIMMPARFTQPWLLLDGIYHW----------------- 242
            .....|.|     |.......||... |.|:......|..||...:.:
Zfish   182 STAFSVDI-----DSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSV 241

  Fly   243 ----------------TK-MANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEI 290
                            || :|.|  |.|||: ||.:.|:..:..:::.::|....|.|.||
Zfish   242 TDFFYAALQKIKSDRDTKTVAKD--NTKKRV-DFLQLMVDSQTGVKHKSDGEHTEKGLSDH---- 299

  Fly   291 SESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPT- 354
                      :|::::..|:.||.::..:.::|..:.|..|||...:...|:...|  .|:||.
Zfish   300 ----------EILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF--PNQAPVD 352

  Fly   355 MTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDP 419
            ...|..|.|::..:.|:|||||....:.|...:.|.:....:|....|.:..||.||....:.:|
Zfish   353 YETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEINGLLIPKDLVVMVPTYALHRDPDYWSEP 417

  Fly   420 EKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL 473
            |.|:||||:..|.|:..||.::||..|||.|||.|||.:.:|..:..:|:.:.:
Zfish   418 ESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDV 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	103/436 (24%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	104/438 (24%)