Protein Alignment Cyp4aa1 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 155/537 - (28%)
• Similarity: 254/537 - (47%)
• Gaps: 100/537 - (18%)

  Fly    15 LCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLG--NCMLVTDKDLMRRCAGKAF 77
            ||.:|:|    |..|..|:....:..::   :...|||:....|  |......|||.|
 Frog    28 LCVVLLL----LKAYALYSRGRRFAAAL---VPFPGPPAHWLYGHVNQFRRDGKDLDR------- 78

  Fly    78 DLYGSLVRIWVLLFP---------FFAVL---EPEDLQVIL---SSKKHTNKVFFYRLMHNFLGD 127
                  :.:||..:|         ||..|   :|:..:|:.   ..|..|.    |..:..::|.
 Frog    79 ------LMVWVNKYPNAFPLWIGKFFGTLIITDPDYAKVVFGRSDPKTSTG----YNFLVPWIGK 133

  Fly   128 GLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDA-----EAVG--------TE 179
            ||:..||:.|..|||||.|.||:::|:.::....|:::.:.:.||.     |:|.        |.
 Frog   134 GLLILSGNTWFQHRRLITPGFHYDVLKPYVSLISDSTKIMLDELDVYSNKDESVELFQHVSLMTL 198

  Fly   180 INIAK----YVNNCVLDILNEAVLGVPIKKRGQDVAMMEDS-----PFRQGKIMMPA----RFTQ 231
            .:|.|    |.:||..|..|:.:..|      .|::.:...     |:....|...:    ||.:
 Frog   199 DSIMKCAFSYHSNCQTDKDNDYIQAV------YDLSWLTQQRIRTFPYHSNLIYFLSPHGFRFRK 257

  Fly   232 PWLLLDGIYHWTKMANDELNQKKRLNDFTRKM--IQRRRQIQNNNNGNSERKCLLDHMI-EISES 293
            ...::.  .|..|:    :.|:|:|.:...::  :|::|.:.           .||.:: ...|:
 Frog   258 ACRIVH--LHTDKV----IGQRKKLLESKEELEKVQKKRHLD-----------FLDILLCSKDEN 305

  Fly   294 NRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTM--T 356
            .:..:.||:..|..|||..|.|:..:.:::.|:.:..:||.|.:|..|::   |......||  .
 Frog   306 GQGLSHEDLRAEVDTFMFEGHDTTSSGISWILYCMATHPEHQQKCREEIS---EALGERQTMEWD 367

  Fly   357 DLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPE 420
            ||:.|.|..|||||:|||||.||.::|:|.:.:.... .:||||..|.:..||.||..:::.|||
 Frog   368 DLNRMPYTTMCIKESLRLYPPVPSVSRELAKPITFHDGRSLPAGMLVSLQIYAIHRNPNVWKDPE 432

  Fly   421 KFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAAT 485
            .|.|.|||||||..||.:||:||:||||.|||..||:.|:|..|:..|:.::|.|...|..:...
 Frog   433 IFDPLRFSPENSSKRHSHAFVPFAAGPRNCIGQNFAMNEMKVAVALTLKRFELSPDLSKPPLKQP 497

  Fly   486 FRITLRASGGLWVRLKE 502
             ::.||:..|:.|.||:
 Frog   498 -QLVLRSKNGIHVYLKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	136/463 (29%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	138/477 (29%)