Protein Alignment Cyp4aa1 and cyp4f22

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_012812356.1
• Gene: cyp4f22 / 548527
• XenbaseID: XB-GENE-5889578
• Length: 545
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 140/535 - (26%)
• Similarity: 250/535 - (46%)
• Gaps: 66/535 - (12%)

  Fly    13 LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLP----FLGN-------CMLV--- 63
            |..|.|:...::.::||.:...:|        :.||...|..|    .||:       |.|:
 Frog    29 LLFCLIMFRTILKMAIYIYAYIIN--------ARRLRCFPEPPRRSWLLGHLGLHPQICALLLLL 85

  Fly    64 ---------TDKDLMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQ--VILSSKKHTNKVFF 117
                     |::.|..  .......:......|:......:::.|:.::  |..|:........|
 Frog    86 CCHCLQFMPTEEGLTE--VSNTISNFRKSFLTWMGPISLVSMVHPDTIKPMVAASAAIAPKDELF 148

  Fly   118 YRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTF---VDASQSLYENLDAEAVG-T 178
            |..:..:|||||:.|.|.||...|||:.||||.::|:.::..|   .|...:.:..|  .||| .
 Frog   149 YGFLRPWLGDGLLLSRGEKWGRQRRLLTPAFHFDILKNYVKIFNQSTDIMLAKWRRL--AAVGPV 211

  Fly   179 EINIAKYVNNCVLDILNEAVLGV--PIKKRGQD--VAMME-DSPFRQGKIMMPARFTQPWLLLDG 238
            .:::.::|:...||.|.:.....  ..:::..|  .|:.| .|...:.:..:|..|       |.
 Frog   212 SLDMFEHVSLMTLDTLLKCTFSYDSDCQEKPSDYIAAIYELSSLVVKREHYLPHHF-------DF 269

  Fly   239 IYHWTKMANDELNQKKRLNDFTRKMIQRRRQ-IQNN------NNGNSERKCLLD-HMIEISESNR 295
            ||:.:..........|.:::||..::|:|:: :|..      .:...:.|..:| .::...|...
 Frog   270 IYNLSSNGRKFHQACKTVHEFTAGVVQQRKKALQEKGIEEWIKSKQGKTKDFIDILLLSKDEDGN 334

  Fly   296 DFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTD-LH 359
            ..::||:..|..|||..|.|:..:.:::.|:.|..:||.|::|..|:..:.|..:......| |.
 Frog   335 QLSDEDMRAEVDTFMFEGHDTTASGLSWILYNLACHPEYQEKCRKEITELLEGKDTKHLEWDELS 399

  Fly   360 EMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQ 423
            ::.:..|||||:|||:|.|..::|:..|:::|.. ..:|.|::..|..|.||....::|:|:.:.
 Frog   400 QLPFTTMCIKESLRLHPPVTAVSRRCTEDIKLPDGKVIPKGNSCLISIYGTHHNPDVWPNPQVYD 464

  Fly   424 PERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVS-RLLRSYQLLPVTGKTTIAATFR 487
            |.||.||..:.|..:||:|||||||.|||..||:.|:|.::: .|...|..|..|  .|:.....
 Frog   465 PYRFDPEKLQERSSHAFVPFSAGPRNCIGQNFAMAEMKIVLALTLYNFYMRLDET--KTVRRKPE 527

  Fly   488 ITLRASGGLWVRLKE 502
            :.|||..|||::::|
 Frog   528 LILRAENGLWLQVEE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	122/438 (28%)
cyp4f22	XP_012812356.1	CYP4F	99..539	CDD:410772	124/452 (27%)