Protein Alignment Cyp4aa1 and cyp51

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001001730.2
• Gene: cyp51 / 414331
• ZFINID: ZDB-GENE-040625-2
• Length: 499
• Species: Danio rerio
• Alignment Length: 518
• Identity: 121/518 - (23%)
• Similarity: 214/518 - (41%)
• Gaps: 80/518 - (15%)

  Fly    11 TNLELCSILI---LLVISLSIYTFYATLNTYLRSVLLSLRLTG------------PPSLPFLGNC 60
            |.||:.|.||   :|.:||:.....|::.|........|..|.            |.||||||..
Zfish     2 TILEVGSQLIESAVLQMSLTSVLLTASVFTLTLGYFSKLLFTQHSSEHTKYPPHIPSSLPFLGQA 66

  Fly    61 MLVTDKDLMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKH-----------TNK 114
            :......:  ....||::.||.:|...::...|..:|..:...::.:||..           |..
Zfish    67 VAFGRSPI--EFLEKAYEQYGPVVSFTMVGKTFTYLLGSDAAALMFNSKNEDLNAEDVYARLTTP 129

  Fly   115 VFFYRLMHN-----FLGDGLITSSG---SKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENL 171
            ||...:.::     ||....:..:|   :::..|..:|:        |:..|.|....:|...||
Zfish   130 VFGKGVAYDVPNPLFLEQKKMLKTGLNIAQFKQHVEIIE--------EETKDYFRRWGESGERNL 186

  Fly   172 -DAEAVGTEINIAKYVNNC-VLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWL 234
             ||.:....:..::.::.| :..:|:|.|        .|..|.: |..|.....::|.     ||
Zfish   187 FDALSELIILTASRCLHGCEIRSLLDERV--------AQLYADL-DGGFTHAAWLLPG-----WL 237

  Fly   235 LLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEIS-ESNRDFT 298
            .|..   :.:.....|..||...:..:|   ||...:.:::       :|..:|:.: :..|..:
Zfish   238 PLPS---FRRRDRAHLEIKKIFYNVIKK---RREDTEKHDD-------ILQTLIDATYKDGRPLS 289

  Fly   299 EEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRY 363
            :::|.......:||||.:.....|:..|.|.::...|:||..|..::..:.........|.::..
Zfish   290 DDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQKSVCGEELPPLHYDQLKDLSL 354

  Fly   364 MEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFS 428
            ::.|:||.|||.|.:..:.|......::.::|:|.|..|.:.|...|||...:.:...|.|:|:.
Zfish   355 LDRCLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQVCVSPTVNHRLQDTWAERLDFDPDRYL 419

  Fly   429 PENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL------LPVTGKTTIAAT 485
            .:|......:|::||.||...|||..||.::||||.|.|||.:..      .|....||:..|
Zfish   420 HDNPAAGEKFAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDFELVDGHFPPVNYTTMIHT 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	98/433 (23%)
cyp51	NP_001001730.2	CYP51-like	80..491	CDD:410668	100/438 (23%)