DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4aa1 and CYP96A10

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001031814.1	Gene:	CYP96A10 / 3770599	AraportID:	AT4G39490	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	135/569 - (23%)
Similarity:	228/569 - (40%)	Gaps:	144/569 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLVISLSIYTFYATLNTYLRSVLLSL---RLTGPPSLPFLGNC--MLVTDKDLMRRCAGKAFDLY 80
            |..||::.:.|     ...|..|::.   ||. |.:.||.|..  :||.        ..:.:|..
plant     6 LFEISIAFFCF-----LLFRHFLINKKTHRLC-PTNWPFFGMIPGLLVE--------IHRVYDFI 56

  Fly    81 GSLVRIWVLLFP----------FFAVLEPEDLQVILSSK-KHTNKVFFYRLMHNFLGDGLITSSG 134
            ..::.:..|.:|          ....::|.::..|:||. .:..|...::.:.:.||||:..:..
plant    57 TEILEVTNLTYPCTGPCFANLDMLVTVDPANIHHIMSSNFANYPKGPEFKKLFDILGDGIFNADS 121

  Fly   135 SKWSNHRRLIQ-------------------------PAFHHNLLEK-------------FIDTFV 161
            ..|.:.|:..|                         |...|...||             |..|||
plant   122 ELWKDLRKSAQSMMMNPEFQKFSLATSLKKLEKGLVPLLDHVAKEKLAVDLQDMFQRFTFDTTFV 186

  Fly   162 DASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMP 226
                 |....|...:..|:...::..  .||...||:.                  ||..|   |
plant   187 -----LATGYDPGCLSVEMPEVEFAR--ALDDAEEAIF------------------FRHVK---P 223

  Fly   227 ARFTQPWLL--LDGIYHWTKMANDELNQKKRLNDFTRK-----MIQRRRQIQNNNNGNSERKCLL 284
            ..|   |.|  |.|:       .||....|..:...|.     .|:|....:..||.:|..|.||
plant   224 EIF---WRLQGLLGL-------GDEKKMTKARSTLDRVCSKYIAIKRDEVSRGTNNVDSHSKDLL 278

  Fly   285 DHMIEISESNRDFTEEDIVNEA---------CTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVL 340
                 .|..|.|.|:..::|.:         .||||||:|:.|:.:.:..:||.:|||...:...
plant   279 -----TSYMNLDTTKYKLLNPSDERFLRDTILTFMLAGRDTTGSGLTWFFWLLIKNPEVIAKIRQ 338

  Fly   341 ELAT-IFE---------DSNRAPTMT--DLHEMRYMEMCIKEALRLYPSVPLIARK-LGEEVRLA 392
            |:.| :|:         ::|.:.:.:  :|.::.|:...|.|:|||||.||...:. ...:|..:
plant   339 EINTALFQRSKVDDDASNNNDSDSFSPQELKKLVYLHGAICESLRLYPPVPFQHKSPTKPDVLPS 403

  Fly   393 KHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPE--NSENRHPYAFLPFSAGPRYCIGNR 454
            .|.:.|.|.:..|.|:..|:..:: .|..:|:|||:..|  ||.:...|.||.|:||||.|:|..
plant   404 GHKVDANSKILFCLYSLGRMKSVWGEDALEFKPERWISESGNSVHEPSYKFLSFNAGPRTCLGKE 468

  Fly   455 FAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKER 503
            .|:|::|::..:::::|::..|.|: .|.....:.|....||.|.:.:|
plant   469 VAMMQMKSVAVKIIQNYEMKIVEGQ-QIEPAPSVILHMKHGLKVTVTKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	119/507 (23%)
CYP96A10	NP_001031814.1	CYP86A	68..509	CDD:410687	115/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920