Protein Alignment Cyp4aa1 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 152/551 - (27%)
• Similarity: 262/551 - (47%)
• Gaps: 95/551 - (17%)

  Fly    18 ILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDL--- 79
            :.|.|.:.| :...|..|:|:.|..:|: :..||..||.:||.      ..|.:...:..|.
  Fly     5 LYIFLALPL-LLVAYLELSTFRRRRVLN-KFNGPRGLPLMGNA------HQMGKNPSEILDTVFS 61

  Fly    80 ----YG--SLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWS 138
                ||  :.| .|:..:....|...:.|:.||||:....|...|:|.|.:||.||:||:||||.
  Fly    62 WWHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWH 125

  Fly   139 NHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEI-NIAKYVNNCVLDILNEAVLGVP 202
            .||::|.||||.|:|:.|.:...:.|....::|...|.|..| :..:..:...||::.:..:||.
  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190

  Fly   203 I--------------KKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMAND---EL 250
            |              |....::.|....|.::.:::.                  ::|.|   ..
  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLY------------------RLAPDYPAYS 237

  Fly   251 NQKKRLNDFTRKMIQRRRQIQ-----NNNNGNS---ERKCLLDHMIEISESNRDFTEEDIVNEAC 307
            ...|.|.|||.::|.:|.:..     :.|.|:.   ::...||.::..:...|....:::..|..
  Fly   238 RTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVS 302

  Fly   308 TFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDS--NRAPTMTDLHEMRYMEMCIKE 370
            |||..|.|:..:.|:|.::||:::.:.|.:...|...:..:|  .|..|..::.:|:|:::.|||
  Fly   303 TFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKE 367

  Fly   371 ALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENR 435
            |.|:|||||.|.|...::..:....:|.|:.:.:..........::.||.||:||||   ..|..
  Fly   368 AQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKP 429

  Fly   436 HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGK---------TTIAA------- 484
            .|:.::|||||||.|||.:||::||||:||:::|::::||...:         |||..
  Fly   430 GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKK 494

  Fly   485 --TFR----------ITLRASGGLWVRLKER 503
              .:|          :||::..||::|||||
  Fly   495 RDPYRHKYDPILSAVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	129/461 (28%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	129/461 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460474
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I1639
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900