Protein Alignment Cyp4aa1 and Cyp4d1

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 151/518 - (29%)
• Similarity: 265/518 - (51%)
• Gaps: 56/518 - (10%)

  Fly    22 LVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDK---DLMRRCAGKAFDLY--- 80
            |.:.|.:|..     .:.|.:.|...:.|||.||.:|:......|   ::::    |.|:..
  Fly    13 LFVGLLLYHL-----KFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVK----KIFEFMETY 68

  Fly    81 --GSLVRIWVLLFPFFAVL--EPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSNHR 141
              ..::::|  |.|...||  .|:|::|:|.:.:..:|...|:.:..:|.:||:.|.|.||...|
  Fly    69 SKDQVLKVW--LGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRR 131

  Fly   142 RLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAV---GTEINIAKYVNNCVLDILNEAVLGVPI 203
            ::|.||||..:|::|::.|...|:.|..|::.:.:   .:..::..::|.|.:|.:.|..:||.|
  Fly   132 KIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSI 196

  Fly   204 KKRGQDVAMMEDSPFRQG----KIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMI 264
            ..:..     .||.:.|.    .:::..|........|..|..|.:|..|......|:.||.|:|
  Fly   197 NAQSN-----ADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKII 256

  Fly   265 -QRRRQI------QNNNN-----GNSERKCLLDHMIEISESNRDFTEEDIVNEACTFMLAGQDSV 317
             |||.::      |.::|     |...:...||.:::.:...|..:..||..|..|||..|.|:.
  Fly   257 VQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTT 321

  Fly   318 GAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTD-LHEMRYMEMCIKEALRLYPSVPLI 381
            .:|:.|..:.:..:||.|.:|..|:.::..:....|...: |:::.|:::|:||.||:||||||:
  Fly   322 SSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLL 386

  Fly   382 ARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFS-PENSENRHPYAFLPFSA 445
            .||:.|:..:....:|||:|:.|.|....|...::.:|..|:||||. ...:|..:|||::||||
  Fly   387 GRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSA 451

  Fly   446 GPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTT-----IAATFRITLRASGGLWVRLKER 503
            |||.|||.:||::|||.||:.:||.|: :...|.::     ||   .:.||....|..:::||
  Fly   452 GPRNCIGQKFAMLEIKAIVANVLRHYE-VDFVGDSSEPPVLIA---ELILRTKEPLMFKVRER 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	138/455 (30%)
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	144/486 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460467
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I1639
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	9	9.000