Protein Alignment Cyp4aa1 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 149/538 - (27%)
• Similarity: 245/538 - (45%)
• Gaps: 110/538 - (20%)

  Fly    23 VISLSIYTFYATLNTYLRSVLLSLRLTGPPSLP-----------------------FLGNCMLVT 64
            ::||.:..|.| :..|||...|...|...||.|                       |.|.|:..
  Rat    24 LLSLFLVLFKA-VQFYLRRQWLLKALEKFPSTPSHWLWGHDLKDREFQQVLTWVEKFPGACLQW- 86

  Fly    65 DKDLMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVIL--SSKKHTNKVFFYRLMHNFL-- 125
                          |.||..|  |||:      :|:.::|:|  |..|.:.   .|:.:..::
  Rat    87 --------------LSGSKTR--VLLY------DPDYVKVVLGRSDPKASG---IYQFLAPWIVS 126

  Fly   126 --GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSL---YENLDAEAVGTEINIAKY 185
              |.||:..:|.||..|.|::.||||:.:|:.::....|:...:   :|.||.:  ...:.|..|
  Rat   127 GTGYGLLLLNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQ--DHPLEIFHY 189

  Fly   186 VNNCVLDIL------NEAVLGVPIKKRGQDVAMMED----------SPFRQGKIMMPARFTQPWL 234
            |:...||.:      ::..:.:.:..|....| :||          |.|....|
  Rat   190 VSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKA-VEDLNNLTFFRVRSAFYGNSI----------- 242

  Fly   235 LLDGIYHWTKMAND-ELNQK--KRLNDFTRKMIQ-RRRQIQNNNNGNSERK----CLLDHMIEIS 291
                ||:   |::| .|:::  :..::.|..:|: |:.|:||.......||    ..||.::...
  Rat   243 ----IYN---MSSDGRLSRRACQIAHEHTDGVIKMRKAQLQNEEELQKARKKRHLDFLDILLFAK 300

  Fly   292 -ESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTM 355
             |..:..::||:..|..|||..|.|:..:.:::..:.|..:||.|:||..|:.:|..|.. :.|.
  Rat   301 MEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGT-SVTW 364

  Fly   356 TDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDP 419
            ..|.::.|..|||||||||||.||.::|:|...|.... .::|.|....|..|..|.....:|:|
  Rat   365 DHLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNP 429

  Fly   420 EKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAA 484
            :.|.|.||||::.  ||.:|:||||.|.|.|||.:||:.|:|..|:..|..::|||...:..:..
  Rat   430 KVFDPSRFSPDSP--RHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPM 492

  Fly   485 TFRITLRASGGLWVRLKE 502
            . |:.|::..|:.:|||:
  Rat   493 A-RLVLKSKNGIHLRLKK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	130/451 (29%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	134/487 (28%)