Protein Alignment Cyp4aa1 and Cyp11a1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 448
• Identity: 82/448 - (18%)
• Similarity: 164/448 - (36%)
• Gaps: 96/448 - (21%)

  Fly    77 FDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFF---YRLMHNFLGD--GLITSSGSK 136
            |..||.:.|..:.......:|:|:|...:.|.:....:.:.   :...|.:...  |::..|...
  Rat    80 FQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVAYHQYYQRPIGVLFKSSDA 144

  Fly   137 WSNHRRLI-QPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLG 200
            |...|.:: |.....:.::.|:......:|...:.|....  .:.|..|:..:...|:...|...
  Rat   145 WRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRI--KQQNSGKFSGDISDDLFRFAFES 207

  Fly   201 VPIKKRGQDVAMMEDSPFRQGKIMMP--ARFTQPWLLLDGIYHWTKMANDELNQK---------- 253
            :.....|:.:.|:|:       |:.|  .||      :|.:|.....:...||..
  Rat   208 ITSVVFGERLGMLEE-------IVDPESQRF------IDAVYQMFHTSVPMLNMPPDLFRLFRTK 259

  Fly   254 -------------KRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTE------ 299
                         .:.:::|:......||                        .|||::
  Rat   260 TWKDHAAAWDVIFSKADEYTQNFYWDLRQ------------------------KRDFSKYPGVLY 300

  Fly   300 ----------EDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPT 354
                      ::|.......:..|.|:....:.:.|:.:..|.:.|:....|:.     :.|...
  Rat   301 SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVL-----AARRQA 360

  Fly   355 MTDLHEM----RYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHI 415
            ..|:.:|    ..::..|||.|||:|....:.|.:..::.|..:.:||.:.|.:..||..|.:..
  Rat   361 QGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMGRESSF 425

  Fly   416 YPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL 473
            :|:|.||.|.|:. |.|:|...:.:|.|..|.|.|:|.|.|.:|:...:..:|.::::
  Rat   426 FPNPNKFDPTRWL-EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRI 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	80/444 (18%)
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:477761	82/448 (18%)