Protein Alignment Cyp4aa1 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 150/505 - (29%)
• Similarity: 253/505 - (50%)
• Gaps: 39/505 - (7%)

  Fly    20 ILLVISLSIYTFYATLNTYLR--SVLLSLR-LTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYG 81
            :.||..|::....| :..|||  .:|..|| ..||.:...||:...:.:.::         :...
  Rat    16 LALVFCLALVLMQA-VKLYLRRQRLLRDLRPFPGPTAHWLLGHQKFLQEDNM---------EKLD 70

  Fly    82 SLVRIWVLLFP--------FFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWS 138
            .:|:.:...||        ||.:.:|:..::.| |:......:.::||..|||.||:...|.:|.
  Rat    71 EIVKEYPCAFPCWVGPFQAFFYIYDPDYAKIFL-SRTDPKTQYLHQLMTPFLGRGLLNLDGPRWF 134

  Fly   139 NHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDA--EAVGTEINIAKYVNNCVLDILNEAVLG- 200
            .||.|:.||||.::|:..:|....:...:.:..:.  ....|.|.:.:::|...|||:.:...|
  Rat   135 QHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQ 199

  Fly   201 -VPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMI 264
             ...:..|...:.:: :.|..|:| :.:|....|...|.|:..:...:......|.::..|.|:|
  Rat   200 ETNCQINGTYESYVK-ATFELGEI-ISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKII 262

  Fly   265 QRRRQI---QNNNNGNSERKCLLDHMIEISESN-RDFTEEDIVNEACTFMLAGQDSVGAAVAFTL 325
            |.|::.   |.|.:.....:..||.::.....: :.|::.|:.:|..|||.||.|:..|::::.|
  Rat   263 QDRKKTLKDQVNQDDTQTSQNFLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLL 327

  Fly   326 FLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVR 390
            :.|..|||.||||..|:.:|..|.: :.|...|.|:.|..|||||.|||.|.:|.|:|:|.:.:.
  Rat   328 YCLALNPEHQDRCRTEIRSILGDGS-SITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLT 391

  Fly   391 LAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNR 454
            |.. |:||||..|.:..:..|....::.||:.|.|.||:.||||.|||.||||||:|||.|||.:
  Rat   392 LPDGHSLPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQ 456

  Fly   455 FAIMEIKTIVSRLLRSYQLLPVTGKTTIAATF--RITLRASGGLWVRLKE 502
            ||::|:|..::..|..::   |....|....|  ...||...|:::.||:
  Rat   457 FAMLELKVAIALTLLRFR---VAADLTRPPAFSSHTVLRPKHGIYLHLKK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	134/435 (31%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	134/449 (30%)