Protein Alignment Cyp4aa1 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 129/538 - (23%)
• Similarity: 227/538 - (42%)
• Gaps: 87/538 - (16%)

  Fly    24 ISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYGSLVRIWV 88
            |.::::::|....|:.|    ...:.||...|.||..:...|.:.       .|.|.   .|.|.
 Worm    12 IFVAVFSYYIWQWTFWR----RRGVVGPMGFPVLGVFLNSLDNNF-------PFPLQ---CREWT 62

  Fly    89 LLF-PFFAVLEPEDLQVILSSKKHTNKVF------FY-RLMHNFLGD-------GLITSSGSKWS 138
            ..| ..:...|.....:::|..:..::||      || |..:...||       .|..:.|.:|.
 Worm    63 KKFGKIYGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQGFRWK 127

  Fly   139 NHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAE-AVGTEINIAKYVNNCVLDILNEAVLGVP 202
            ..|.:..|.|.::.|.|...|..|::..|..:::.: |.|.:|::.|:.....||::....:|..
 Worm   128 RLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIAMGQT 192

  Fly   203 IKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIY--------HWTKMANDELNQKKRLNDF 259
            ..:..::..|...|...||..   |:.    .|:.||:        ....:.|.::...:::|:.
 Worm   193 DSQMFKNPIMPIVSKLFQGNF---AKL----FLIGGIFPTFLVEIIRQILLKNLKVGSFRKINEI 250

  Fly   260 T----RKMIQRRRQIQNNNNGNSERKCLLDHMIE--------ISESNRDF-----------TEED 301
            |    ...|::|.:.|.|.....|....:|..::        ..|:|.||           |.|:
 Worm   251 TLDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTEE 315

  Fly   302 IVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEM 366
            ||.:...|::||.|:...::::..:||..:||.|.:...|:..  |..|...|:..|.:::|||.
 Worm   316 IVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNR--ECPNPEVTIDQLSKLKYMEC 378

  Fly   367 CIKEALRLYPSVPLI-ARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSP 429
            ..||||||||..... :|:.....:|....:..|:.:.:..:..|...:|: .|.|.|:|||:..
 Worm   379 VFKEALRLYPLGAFANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQT 443

  Fly   430 ENSENRHPYA-FLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRAS 493
            .||:..:..: ::||..|||.|||.|.|.||.|.::..:||.:..  .||..|     .|.|:..
 Worm   444 PNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTF--ETGAKT-----EIPLKLI 501

  Fly   494 G-------GLWVRLKERD 504
            |       .:|:.|..|:
 Worm   502 GRATTQPESVWMHLNPRN 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	114/473 (24%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	112/461 (24%)