Protein Alignment Cyp4aa1 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 488
• Identity: 129/488 - (26%)
• Similarity: 223/488 - (45%)
• Gaps: 58/488 - (11%)

  Fly    12 NLELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDK--DLMRRCAG 74
            |:.|.:.::|..|.:.:|.:    .|........|.::||..|||:||.:.....  :..|.|..
  Rat     6 NISLETWMLLATILVLLYLY----GTSTHGNFKKLGISGPKPLPFVGNILAYRHGFWEFDRHCHK 66

  Fly    75 KAFDLYGSLVRIWVLLF-----PFFAVLEPEDLQVILSSKKH---TNKVFFYRLMHNFLGDGLIT 131
            |..|::|         |     |..|:.:|:.::.:|..:.:   ||:..|...  ..|...:..
  Rat    67 KYGDIWG---------FYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPA--GILKKAITL 120

  Fly   132 SSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEA-VGTEINIAKYVNNCVLDILN 195
            |...:|...|.|:.|.|....|::........:..|.:|:..|| .|..|.:........:|::.
  Rat   121 SEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGAYSMDVIT 185

  Fly   196 EAVLGVPIKKRGQDVAMMEDSPFRQG-KIMMPARFTQPWLL-------LDGIYHWTKMANDELNQ 252
            ....||.:     |......:||.|. |.::...|..|:.|       |..::.    |.|....
  Rat   186 GTSFGVNV-----DSLNNPQNPFVQKVKKLLKFNFLDPFFLSVILFPFLTPVFE----AFDITVF 241

  Fly   253 KKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDH---MIEI-----SESNRDFTEEDIVNEACTF 309
            .|.:..|.|..::|.::    |....:.|..||.   ||..     .||::..|:.:||.::..|
  Rat   242 PKDVMKFFRTSVERMKE----NRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIFF 302

  Fly   310 MLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTD-LHEMRYMEMCIKEALR 373
            :.||.::..:|::|.|:||..:|:.|.:...|:....  .|:||...| |.||.|::|.:.|.||
  Rat   303 IFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAAL--PNKAPVTYDVLVEMEYLDMVLNETLR 365

  Fly   374 LYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPY 438
            |:|....:.|...::|.:....:|.|:.|.:..:|.|:....:|:||:|.||||..:|.::.:||
  Rat   366 LFPVGGRLERVCKKDVEINGVFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSINPY 430

  Fly   439 AFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSY 471
            .:|||..|||.|||.|||:|.:|..:.|:|:::
  Rat   431 IYLPFGNGPRNCIGMRFALMNMKIALVRVLQNF 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	111/417 (27%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	113/423 (27%)