Protein Alignment Cyp4aa1 and Cyp51

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 522
• Identity: 123/522 - (23%)
• Similarity: 211/522 - (40%)
• Gaps: 88/522 - (16%)

  Fly     5 KVLERTT--NLELCSILILLVISLS-IYTFYATLNTYLRSVLLSLRLTGPP----SLPFLGNCML 62
            :.:|:.|  || |.::||....:|| :|.|...:.   ..|.|......||    .:||||:.:
Mouse    16 QAMEQVTGGNL-LSTLLIACAFTLSLVYLFRLAVG---HMVQLPAGAKSPPHIYSPIPFLGHAI- 75

  Fly    63 VTDKDLMRRCAGK--------AFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKH-------- 111
                     ..||        |::.||.:....::...|..:|..:...::.:||..
Mouse    76 ---------AFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVY 131

  Fly   112 ---TNKVFFYRLMHN-----FLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLY 168
               |..||...:.::     ||....|..||...::.::.: |.......|.|        ||..
Mouse   132 GRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYV-PIIEKEAKEYF--------QSWG 187

  Fly   169 ENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKR-GQDVAMME---DSPFRQGKIMMPARF 229
            |:       .|.|:.:.::..::...:..:.|..|:.: .:.||.:.   |..|.....::||
Mouse   188 ES-------GERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWLLPA-- 243

  Fly   230 TQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESN 294
               ||.|...     ...|..:  :.:.:...|.||:||  .:........:.|||   ...:..
Mouse   244 ---WLPLPSF-----RRRDRAH--REIKNIFYKAIQKRR--LSKEPAEDILQTLLD---STYKDG 293

  Fly   295 RDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLH 359
            |..|:|:|.......:||||.:.....|:..|.|.::...|::|.||...:..:.....|...|.
Mouse   294 RPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLK 358

  Fly   360 EMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQP 424
            ::..::.||||.|||.|.:..:.|.......:|.:|:|.|..|.:.|....||...:.:...|.|
Mouse   359 DLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNP 423

  Fly   425 ERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL------LPVTGKTTIA 483
            :|:..:|..:...:|::||.||...|:|..||.::||||.|.:||.|:.      .|....||:.
Mouse   424 DRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFPTVNYTTMI 488

  Fly   484 AT 485
            .|
Mouse   489 HT 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	100/431 (23%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	102/436 (23%)