Protein Alignment Cyp4aa1 and Cyp51

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 522
• Identity: 123/522 - (23%)
• Similarity: 211/522 - (40%)
• Gaps: 88/522 - (16%)

  Fly     5 KVLERTT--NLELCSILILLVISLS-IYTFYATLNTYLRSVLLSLRLTGPP----SLPFLGNCML 62
            :.:|:.|  || |.::||....:|| :|.|...:.   ..|.|......||    .:||||:.:
Mouse    16 QAMEQVTGGNL-LSTLLIACAFTLSLVYLFRLAVG---HMVQLPAGAKSPPHIYSPIPFLGHAI- 75

  Fly    63 VTDKDLMRRCAGK--------AFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKH-------- 111
                     ..||        |::.||.:....::...|..:|..:...::.:||..
Mouse    76 ---------AFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVY 131

  Fly   112 ---TNKVFFYRLMHN-----FLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLY 168
               |..||...:.::     ||....|..||...::.::.: |.......|.|        ||..
Mouse   132 GRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYV-PIIEKEAKEYF--------QSWG 187

  Fly   169 ENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKR-GQDVAMME---DSPFRQGKIMMPARF 229
            |:       .|.|:.:.::..::...:..:.|..|:.: .:.||.:.   |..|.....::||
Mouse   188 ES-------GERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWLLPA-- 243

  Fly   230 TQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESN 294
               ||.|...     ...|..:  :.:.:...|.||:||  .:........:.|||   ...:..
Mouse   244 ---WLPLPSF-----RRRDRAH--REIKNIFYKAIQKRR--LSKEPAEDILQTLLD---STYKDG 293

  Fly   295 RDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLH 359
            |..|:|:|.......:||||.:.....|:..|.|.::...|::|.||...:..:.....|...|.
Mouse   294 RPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLK 358

  Fly   360 EMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQP 424
            ::..::.||||.|||.|.:..:.|.......:|.:|:|.|..|.:.|....||...:.:...|.|
Mouse   359 DLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNP 423

  Fly   425 ERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQL------LPVTGKTTIA 483
            :|:..:|..:...:|::||.||...|:|..||.::||||.|.:||.|:.      .|....||:.
Mouse   424 DRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFPTVNYTTMI 488

  Fly   484 AT 485
            .|
Mouse   489 HT 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	106/462 (23%)
Cyp51	NP_064394.2	p450	67..477	CDD:299894	104/452 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1934
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.860