Protein Alignment Cyp4aa1 and Cyp4b1

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 514
• Identity: 146/514 - (28%)
• Similarity: 239/514 - (46%)
• Gaps: 57/514 - (11%)

  Fly    17 SILILLVISLSIYTFYATLNTYLRSVLLSLRL---TGPPSLPFLGNCMLVTDKDLMRRCAGKAFD 78
            |::||:|..|.:      |:...|...|:..|   .|||.....|:.:.:...
Mouse    18 SVVILMVTVLKL------LSLLFRRQKLARALDSFPGPPKHWLFGHALEIQKT------------ 64

  Fly    79 LYGSLVRI--WVLLFP------------FFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGL 129
              |.|.::  |...||            |..:.||:..:.:. |:......:.|.....::|.||
Mouse    65 --GGLDKVVTWTEQFPYAHPLWLGQFIVFLNIYEPDYAKAVY-SRGDPKAAYVYDFFLQWIGKGL 126

  Fly   130 ITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEA-VGTEINIAKYVNNCVLDI 193
            :...|.||..||:|:.|.||:::|:.::..|.::::.:.:..:.:| .....:|...|.:..||.
Mouse   127 LVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDT 191

  Fly   194 LNEAVLGVPIKKRGQDVAMMEDSPFRQG----KIMMPARFTQPWLLLDGIYHWTKMANDELNQKK 254
            |.:...|     :|.......|:.:...    .::|..|........|.||..|......|...:
Mouse   192 LMKCTFG-----KGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACQ 251

  Fly   255 RLNDFTRKMIQRRR---QIQNNNNGNSERKCL--LDHMIEI-SESNRDFTEEDIVNEACTFMLAG 313
            ..:|.|..:|::|:   |.:.......||:.|  ||.::.. .||....::.|:..|..|||..|
Mouse   252 IAHDHTDHVIRQRKAALQDEKEQKKLQERRHLDFLDILLGARDESGIKLSDADLRAEVDTFMFEG 316

  Fly   314 QDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSV 378
            .|:..:.:::.|:.:...|..|.||..|:..|..|.: :....||.:|.|:.||:||..||||.|
Mouse   317 HDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRD-SFQWDDLAQMTYLTMCMKECFRLYPPV 380

  Fly   379 PLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLP 442
            |.:.|:|.:.|.... .:|||||.:.:..||.||.:.::||||.|.|.||||||...|||:||:|
Mouse   381 PQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFMP 445

  Fly   443 FSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLK 501
            ||||||.|||.:||:.|:|.:.:..|..::..|...|..|... ::.||:..|:.:.||
Mouse   446 FSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVP-QLILRSKNGIHLYLK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	129/450 (29%)
Cyp4b1	NP_031849.1	p450	47..500	CDD:278495	135/474 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750