Protein Alignment Cyp4aa1 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 523
• Identity: 144/523 - (27%)
• Similarity: 252/523 - (48%)
• Gaps: 67/523 - (12%)

  Fly    13 LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAF 77
            |::.|:|.||::.:....||......|::.   .:...||...|.|:.....|::|..
Mouse    19 LQVASVLGLLLLLVKAVQFYLHRQWLLKAF---QQFPSPPFHWFFGHEKFKGDQELQE------- 73

  Fly    78 DLYGSLVRIWVLLFP--------FFAVLEPEDLQVILS-SKKHTNKVFFYRLMHNFLGDGLITSS 133
              ..|.:..:...||        :..|.:|:.::|||. |....|..  |||:..::|.||:..:
Mouse    74 --IVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGA--YRLLAPWIGYGLLLLN 134

  Fly   134 GSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEA-VGTEINIAKYVNNCVLDILNEA 197
            |..|..|||::.||||:::|:.::....|:.:.:.:..:..| ..:.|.|.::::...||    .
Mouse   135 GQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLD----T 195

  Fly   198 VLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMAN--------DELNQKK 254
            |:......:|   ::..|..:|        .:.|....|:.::| :::.|        .:|:...
Mouse   196 VMKCAFSHKG---SVQVDGNYR--------TYLQAIGDLNNLFH-SRVRNIFHQNDTIYKLSSNG 248

  Fly   255 RL--------NDFTRKMIQ-RRRQIQNNNN----GNSERKCLLDHMIEISESNRD-FTEEDIVNE 305
            ||        :|.|..:|: |:.|:|:...    ....|...||.::.....|.| .:::|:..|
Mouse   249 RLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAE 313

  Fly   306 ACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKE 370
            ..|||..|.|:..:.|::..:.|..:|:.|.||..|:.::..|.: :.|...|.::.|..|||||
Mouse   314 VDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGS-SITWDHLDQIPYTTMCIKE 377

  Fly   371 ALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSEN 434
            ||||||.||.|.|:|...|.... .:||.|..|.:..|..|....::|:||.|.|.||:|::.
Mouse   378 ALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSP-- 440

  Fly   435 RHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVR 499
            ||.::|||||.|.|.|||.:||:.|:|.||:..|..::|||...:..:... |:.|::..|:::.
Mouse   441 RHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLA-RLVLKSKNGIYLH 504

  Fly   500 LKE 502
            ||:
Mouse   505 LKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	128/449 (29%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	129/463 (28%)