Protein Alignment Cyp4aa1 and LOC1277762

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_317256.4
• Gene: LOC1277762 / 1277762
• VectorBaseID: AGAMI1_002278
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 542
• Identity: 142/542 - (26%)
• Similarity: 236/542 - (43%)
• Gaps: 97/542 - (17%)

  Fly    13 LELCSILI-LLVISLSIYTFYATLNTYLRSVLLSLRLT------GPPSLPFL--GNCMLVTDKDL 68
            :|...||| ::::.|::|            .||..|..      .|.|.|.|  ||   |.:...
Mosquito     1 MEPLDILISVVMLCLAVY------------FLLDRRFQYWTDRGVPQSKPELVFGN---VREVSR 50

  Fly    69 MRRCAGKAFDLYGS------LVRIWVLLFPFFAVLEPEDLQVIL--SSKKHTNKVFFYRLMHNFL 125
            ....|.|..::|..      ||.:::...|...:.:.|.|:.:.  ..:...::..:|...|:.|
Mosquito    51 TIHLADKFREIYNELKGKHPLVGVYLFFKPVALITDLELLKCVFVKDFQYFHDRGTYYNEKHDPL 115

  Fly   126 GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDA--------SQSLYENLDAEAVGTEINI 182
            ...|....|.||.|.|..:.|.|....::....|.|.|        .::::|.:|.|....   :
Mosquito   116 TAHLFNIEGQKWKNLRNKLSPTFTSGKMKMMFSTIVAAGKQFKDFMEETVHEQVDFELKDV---L 177

  Fly   183 AKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMAN 247
            |::..    |::.....|:.......     .|:.||   :|....|::|         ..|:.:
Mosquito   178 ARFTT----DVIGMCAFGIECNSMRN-----PDAEFR---VMGRKIFSKP---------RGKVKS 221

  Fly   248 DELNQKKRL-------------NDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEI---SESNRD 296
            ..:|...||             :||....:  |..|:.....|.:|...:|.:|.:   .|:..|
Mosquito   222 LVINSMPRLAKLIGLRTLDPEVSDFFMNAV--RDTIKYRVENNVQRNDFMDILIRMRSDKETKSD 284

  Fly   297 ---FTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQD---RCVLELATIFEDSNRAPTM 355
               .|..:|..:|..|.|||.::....:.|||:.|..|.|.||   |||.::.|   ..|...|.
Mosquito   285 DGTLTFNEIAAQAFVFFLAGFETSSTLLTFTLYELALNQEVQDKGRRCVKDVLT---KHNGELTY 346

  Fly   356 TDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRL--AKHTLPAGSNVFICPYATHRLAHIYPD 418
            ..:.||.|::..:||:||.||.||:..|:..::.::  .|..|.||::|.:..:|.||....:||
Mosquito   347 DAVMEMNYLDQILKESLRKYPPVPVHFRETSKKYQVPGTKTVLEAGTSVMVPVHAIHRDPEHFPD 411

  Fly   419 PEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIA 483
            ||:|.|:||:.|....|||||:.||..|||.|||.||.:|:.:..::.||..::..| :.||.:.
Mosquito   412 PERFDPDRFTAEQEAKRHPYAWTPFGEGPRICIGLRFGMMQARIGLAYLLTGFRFTP-SAKTIVP 475

  Fly   484 ATFRI---TLRASGGLWVRLKE 502
            ..|.|   .|..:||||:::::
Mosquito   476 MEFDIKSFILSPAGGLWLKVEK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	122/459 (27%)
LOC1277762	XP_317256.4	None