Protein Alignment Cyp4aa1 and LOC1273103

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_312050.1
• Gene: LOC1273103 / 1273103
• VectorBaseID: AGAMI1_012639
• Length: 509
• Species: Anopheles gambiae
• Alignment Length: 543
• Identity: 125/543 - (23%)
• Similarity: 220/543 - (40%)
• Gaps: 97/543 - (17%)

  Fly    17 SILILLVISLSI-YTFYATLNTYLRSVLLSLRLTGPPSLP---FL-----GNCMLVTDKDL---M 69
            ::|...:.::|| |.|....:.|.:.       .|.|..|   ||     |........|:   :
Mosquito     6 AVLAAFIFAVSIVYLFIRNKHNYWKD-------NGFPYAPNPHFLFGHAKGQAQTRHGADIHQEL 63

  Fly    70 RRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSS- 133
            .|...:..:.||.:.:   .:.|...|::||..:.||        |..:.:.|:   .|:.|::
Mosquito    64 YRYFKQRGERYGGISQ---FIVPSVLVIDPELAKTIL--------VKDFNVFHD---HGVFTNAK 114

  Fly   134 ------------GSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYV 186
                        |..|...|:.:.|.|....:::...|..|....|.:.::......|:.:...:
Mosquito   115 DDPLTGHLFALEGQPWRLMRQKLTPTFTSGRMKQMFGTIWDVGIELEKCMEQSYNQPEVEMKDIL 179

  Fly   187 NNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQ---------GKIMMPARFTQPWLLLDGIYHW 242
            .....|::.....|:..     :.....||.||:         ..|||.......:..|....|.
Mosquito   180 GRFTTDVIGTCAFGIEC-----NTLKTTDSEFRKYGNKAFELNTMIMMKTFLASSYPTLVRNLHM 239

  Fly   243 TKMAND----------------ELNQKKRLNDFTRKMIQ--RRRQIQNNNNGNSERKCLLDHMIE 289
            ....||                |.|..|| |||...|:|  .:.::.::::|:
Mosquito   240 KITYNDVERFFLDIVKETVDYREANNVKR-NDFMNLMLQIKNKGKLDDSDDGS------------ 291

  Fly   290 ISESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPT 354
            :.:.....|:.::..:|..|.|||.::.....:|.|:.|.:||:.|:|...|:.....::....|
Mosquito   292 LGKGEVGMTQNELAAQAFVFFLAGFETSSTTQSFCLYELAKNPDIQERLREEINRAIAENGGEVT 356

  Fly   355 MTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRL--AKHTLPAGSNVFICPYATHRLAHIYP 417
            ...:..::|::..|.|.||.||.|..:.|....:..:  .||.:|..:.|.|..||..|....||
Mosquito   357 YDVVMNIKYLDNVIDETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPAYAIQRDPDHYP 421

  Fly   418 DPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTI 482
            |||:|.|:||.||..:.|||:.|:||..|||.|||.||.:|:.|..:..|||.::..| :.:|..
Mosquito   422 DPERFNPDRFLPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKFRFSP-SARTPE 485

  Fly   483 AATF---RITLRASGGLWVRLKE 502
            ...:   .||:....|.::::::
Mosquito   486 RVEYDPKMITIAPKAGNYLKVEK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	110/461 (24%)
LOC1273103	XP_312050.1	CYP6-like	70..501	CDD:410679	110/463 (24%)