Protein Alignment Cyp4aa1 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 118/592 - (19%)
• Similarity: 200/592 - (33%)
• Gaps: 177/592 - (29%)

  Fly    19 LILLVISLSIYTFYATLNTYLRSVLL--------SLRL-------------TGPPSLPFLGNCM- 61
            :.||.||.:.: |.|.|.:.|..|||        |||.             .|....||.|..:
 Frog     1 MFLLEISYTSF-FEAALTSALSLVLLLAASHQLWSLRWHSTRDRGSSLPLPKGSMGWPFFGETLH 64

  Fly    62 -LVTDKDLMRRCAGKAF-----DLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRL 120
             ||         .|.:|     :.||::.:..:|..|...|...|:::.||..:.|.....:.:.
 Frog    65 WLV---------QGSSFHSSRREKYGNIFKTHLLGKPVIRVTGAENIRKILLGEHHLVSTQWPQS 120

  Fly   121 MHNFLGDGLITSS-GSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAK 184
            ....||...:::| |......|:::........||.::....:|.:....:. ...|| .:::..
 Frog   121 TQIILGSNTLSNSIGELHRQKRKMMSKVLSSAALESYLPRIHEAVRWEVRSW-CRGVG-PVSMLS 183

  Fly   185 YVNNCVLDILNEAVLGVPIKKRGQDVAMME-DSPFRQGKIMMPARFTQPWLLLD----GIYHWTK 244
            ........|....:||:.:    .|....| ...|.|   ::...|..|   ||    |:....|
 Frog   184 CAKALTFRIAARILLGLSL----TDTQFQELTRTFEQ---LVENLFCLP---LDIPFSGLRKGMK 238

  Fly   245 MANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKC--LLDHMI-EISESNRDFTEEDIVNEA 306
             |.|.|:|  .:.:..::.:.:|          ....|  .||::| ...|..::...:::...|
 Frog   239 -ARDTLHQ--YMEEAIKEKLSKR----------DPDACEDALDYLINSAKEGGKEINMQELKESA 290

  Fly   307 CTFMLAG-QDSVGAAVAFTLFLL----------------------------TQNPE--------- 333
            ...:.|. ..:..|:.:..|.||                            |:||.
 Frog   291 IELIFAAFLTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPATENPNNNILQDNGH 355

  Fly   334 ------CQDRCVL----ELATIFED--------------------------------------SN 350
                  ||...|:    ::.|::|.                                      ||
 Frog   356 QCLTAGCQLPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGENRIQEAPCSHDKSN 420

  Fly   351 RAP------------------TMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLP 397
            .:|                  ::..|..:.|::..:||.|||.|.|....|...:...|..:.:|
 Frog   421 CSPVPGKLQNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRTALQTFELDGYQIP 485

  Fly   398 AGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENR-HPYAFLPFSAGPRYCIGNRFAIMEIK 461
            .|.:|......||..|.:|.:.|.|.|||||.|..|.: ..:.::||..|.|.|||...|.:.:|
 Frog   486 KGWSVMYSIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNYIPFGGGARSCIGKELAQIILK 550

  Fly   462 TIVSRLL 468
            .:...|:
 Frog   551 ILAMELV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	95/502 (19%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	101/533 (19%)