Protein Alignment Cyp4aa1 and Cyp4a32

DIOPT Version :9

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 534
• Identity: 148/534 - (27%)
• Similarity: 256/534 - (47%)
• Gaps: 89/534 - (16%)

  Fly    13 LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAF 77
            |::.|:|.||::.:....||......|:::   .:...||...|.|:.....:::|..
Mouse    19 LQVASVLGLLLLLVKAVQFYLHRKWLLKAL---QQFPSPPFHWFFGHEQFKGEQELKE------- 73

  Fly    78 DLYGSLVRIWVLLFP--------FFAVLEPEDLQVILS-SKKHTNKVFFYRLMHNFLGDGLITSS 133
              ..|.:..:...||        :..|.:|:.::|||. |....|.:  |||:..::|.||:..:
Mouse    74 --VVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSDPKANGI--YRLLAPWIGYGLLLLN 134

  Fly   134 GSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSL---YENLDAEAVGTEINIAKYVNNCVLDILN 195
            |..|..|||::.||||:::|:.::....|:.:.:   :|.|..:  .:.|.|.::::...||
Mouse   135 GQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQ--DSSIEIFQHISLMTLD--- 194

  Fly   196 EAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDG------------IYHWTKMAND 248
                           .:|:.:...:|.:.:...: :.:|...|            |:|    .||
Mouse   195 ---------------TVMKCAFSHKGSVQVDGNY-KTYLQAIGDLNNLFHSRVRNIFH----QND 239

  Fly   249 ---ELNQKKRL--------NDFTRKMIQRRR-QIQNNNN-GNSERKCLLDHMIEI-----SESNR 295
               .|:...||        :|.|..:|:.|: |:|:... .|.::|..|| .::|     .|:..
Mouse   240 TIYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLD-FLDILLFARMENGD 303

  Fly   296 DFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHE 360
            ..:::|:..|..|||..|.|:..:.|::..:.|..:||.|.||..|:.::..|.: :.|...|.:
Mouse   304 SMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGS-SITWDHLDQ 367

  Fly   361 MRYMEMCIKEALRLYPSVPLIARKLGEEVRLAK-HTLPAGSNVFICPYATHRLAHIYPDPEKFQP 424
            :.|..|||||||||||.||.|.|:|...|.... .:||.|..|.:..|..|....::|:||.|.|
Mouse   368 IPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDP 432

  Fly   425 ERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATF-RI 488
            .||:|::.  ||.::|||||.|.|.|||.:||:.|:|.||:..|..::|||  ..|.:.... ||
Mouse   433 SRFAPDSP--RHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLP--DPTRVPEPLARI 493

  Fly   489 TLRASGGLWVRLKE 502
            .|::..|:::.||:
Mouse   494 VLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	131/467 (28%)
Cyp4a32	NP_001093651.1	p450	52..503	CDD:278495	138/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844987
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750