Protein Alignment Cyp4aa1 and cyp8b1.2

DIOPT Version :10

• Sequence 1: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001103758.1
• Gene: cyp8b1.2 / 100004274
• ZFINID: ZDB-GENE-080212-9
• Length: 514
• Species: Danio rerio
• Alignment Length: 537
• Identity: 110/537 - (20%)
• Similarity: 207/537 - (38%)
• Gaps: 144/537 - (26%)

  Fly    18 ILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSL-----PFLGNCMLVTDKD---LMRRCAG 74
            :.|||.:.||:......|..:.|      |.||.|.|     |:|| |:|...||   .::|...
Zfish     5 VQILLALLLSVIGALYLLGGFRR------RRTGEPPLEKGLIPWLG-CVLEFRKDTVKFLQRMKA 62

  Fly    75 KAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKK----HTN-------KVFFY---RLMHNF- 124
            |..|::  .|::....|.|  :.:|:....::...:    .||       :||.|   .:.|.|
Zfish    63 KHGDIF--TVQLGGFYFTF--ITDPQSFGAVVKESRAKLDFTNFADQLVERVFGYGAVEIKHKFF 123

  Fly   125 -----------LGDGLITSSGSKWSNHRRLIQP----------------AFHHNLLEKFIDTFVD 162
                       :||||:..:.:...|.:.|:..                |:.:|::      |..
Zfish   124 KNLQTTSTKHLMGDGLVVMTQAMMYNLQNLMLHSVGSGNGKVWQESGLFAYSYNIV------FRA 182

  Fly   163 ASQSLYENLDAEAVGTE-INIAKYVNNCVLDILNEAVLGVPIKKRGQ---DVAMMEDSPFRQGKI 223
            ...||:.|...:..|.| :..||.:     |:.:...|....:|..|   ::|.....|  :||:
Zfish   183 GYLSLFGNESPKGTGKESVEKAKEI-----DLQHSNDLFWEFRKYDQLFPNLAYGVLGP--RGKM 240

  Fly   224 MMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNG--NSERKCLLDH 286
                                     |..:.|||  |...:..::.:.::|.:|  :.:::...:|
Zfish   241 -------------------------EAERLKRL--FWNMLSVQKMKARDNVSGWVSDQQQVRAEH 278

  Fly   287 MIEISESNRDFTEEDIVNEACTFML--AGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDS 349
            .:           ::.:.:...|:|  |.|.:.|.:..:.|..|.::||.......|:..|.:::
Zfish   279 GM-----------QEFMQDRFMFLLLWASQGNTGPSAFWLLLYLMKHPEAMSAVRKEVEEILKEA 332

  Fly   350 NR----APTMTDLH-----EMRYMEMCIKEALRLYPSVPLIARKLGEEVRL-----AKHTLPAGS 400
            .:    ...:.||.     :...::..::|.||| .:.||:.|.:.|::.:     .::.:..|.
Zfish   333 GQEVKPGGPLIDLSRDMLLKTPILDSAVEETLRL-TTAPLLTRGVMEDMTIIMANGQEYKIREGD 396

  Fly   401 NVFICPYATHRLAHIYPDPEKFQPERFSPENSENRH---------PYAFLPFSAGPRYCIGNRFA 456
            .|.:.||..|....::|||..|:.:||...:...:.         .|..:|:.||...|.|..||
Zfish   397 RVSVFPYLVHIDPEVHPDPLTFKYDRFLNADGSRKTDFYKDGKKLKYYSMPWGAGTTMCPGRFFA 461

  Fly   457 IMEIKTIVSRLLRSYQL 473
            ..|:|..|..:|..:.|
Zfish   462 TNELKQFVFLMLSYFDL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	88/466 (19%)
cyp8b1.2	NP_001103758.1	Cyp8B1	57..508	CDD:410726	91/478 (19%)