DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8299 and KLK15

DIOPT Version :9

Sequence 1:NP_611066.1 Gene:CG8299 / 36751 FlyBaseID:FBgn0034052 Length:260 Species:Drosophila melanogaster
Sequence 2:NP_059979.2 Gene:KLK15 / 55554 HGNCID:20453 Length:256 Species:Homo sapiens


Alignment Length:265 Identity:83/265 - (31%)
Similarity:135/265 - (50%) Gaps:31/265 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LFLLAALGVVILTDSASISTHIVGGDQADIADFPYQVSV----RLETYMLLHICGGSIYAPRVVI 67
            ::||..|..::.:.:|.....::.||:......|:||::    |..       ||.|:.:|..|:
Human     1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFN-------CGASLISPHWVL 58

  Fly    68 TAAHCIKGRYASYIRIVAGQNSI--ADLEEQGVKVSKLIPHAGYNKKTYVNDIGLIITREPLEYS 130
            :||||    .:.::|:..|::::  .|..||....|::|||..|..:::.|||.|:...:|...:
Human    59 SAAHC----QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLN 119

  Fly   131 ALVQPIAVALEAPPSGAQAVVSGWGKRAEDDE----------ALPAMLRAVELQIIEKSTCGAQY 185
            ..|:|..:....|..|...||||||..:.::.          :||..|....:.||..::|...|
Human   120 PQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSY 184

  Fly   186 LTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHI 249
            ..:   :|:.|:|||....|.::|.|||||||...|:|.|:|||| |.|.....|||||.|..::
Human   185 PGR---LTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYL 246

  Fly   250 DWIEE 254
            :||.|
Human   247 EWIRE 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8299NP_611066.1 Tryp_SPc 27..252 CDD:214473 76/241 (32%)
Tryp_SPc 28..255 CDD:238113 79/244 (32%)
KLK15NP_059979.2 Tryp_SPc 25..249 CDD:214473 76/237 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm41500
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.920

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