Protein Alignment CG8299 and HGFAC

DIOPT Version :10

• Sequence 1: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 80/252 - (31%)
• Similarity: 118/252 - (46%)
• Gaps: 39/252 - (15%)

  Fly    28 IVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIK-GRYASYIRIVAGQ---N 88
            |:||..:.....|:..::    |:....|.||:.....|::||||.. ......:.:|.||   |
Human   415 IIGGSSSLPGSHPWLAAI----YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFN 475

  Fly    89 SIADLEEQGVKVSKLIPHAGYNKKTYVNDIGLIITR------EPLEYSALVQPIAVALEAP---- 143
            ...|: .|...:.|.||:..|:... .:|..|::.|      .....|..||||  .|..|
Human   476 RTTDV-TQTFGIEKYIPYTLYSVFN-PSDHDLVLIRLKKKGDRCATRSQFVQPI--CLPEPGSTF 536

  Fly   144 PSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTC------GAQYLTKDYTVTDEMLCAGYL 202
            |:|.:..::|||...|:.....:.||...:.::....|      ||.       ::..||||||.
Human   537 PAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD-------ISPNMLCAGYF 594

  Fly   203 EGGKDTCNGDSGGPLAVD--GV--LVGVVSWGVGCGREGFPGVYTSVNSHIDWIEEQ 255
            :...|.|.||||||||.:  ||  |.|::|||.||||...|||||.|.:::|||.::
Human   595 DCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDR 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	78/247 (32%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	80/249 (32%)