DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8299 and Klk1c3

DIOPT Version :9

Sequence 1:	NP_611066.1	Gene:	CG8299 / 36751	FlyBaseID:	FBgn0034052	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001258244.1	Gene:	Klk1c3 / 292872	RGDID:	735032	Length:	255	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	98/260 - (37%)
Similarity:	136/260 - (52%)	Gaps:	28/260 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LFLLAALGVVILTDSASI-STHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAA 70
            |||..:||.:   |:|.. .:.:|||.:.:....|:||:|..|     .:|||.:..|..|||||
  Rat     6 LFLALSLGQI---DAAPPGQSRVVGGFKCEKNSQPWQVAVINE-----DLCGGVLIDPSWVITAA 62

  Fly    71 HCIKGRYASYIRIVAGQNSIADLEEQGVKVSKLIPHAGY----------NKKTYVNDIGLIITRE 125
            ||    |:....::.|||:::: :.|...||:...|..|          ..|.|.||:.|:...|
  Rat    63 HC----YSDNYHVLLGQNNLSE-DVQHRLVSQSFRHPDYKPFLMRNHTRKPKDYSNDLMLLHLSE 122

  Fly   126 PLEYSALVQPIAVALEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDY 190
            |.:.:..|:.|.:..:.|..|:..:|||||.....:...|..|:.|.:.::....|...|..|
  Rat   123 PADITDGVKVIDLPTKEPKVGSTCLVSGWGSTNPSEWEFPDDLQCVNIHLLSNEKCIKAYKEK-- 185

  Fly   191 TVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEE 254
             |||.|||||.||||||||.|||||||..||||.|:.||| |.||....||:||.:.....||:|
  Rat   186 -VTDLMLCAGELEGGKDTCRGDSGGPLICDGVLQGITSWGSVPCGEPNKPGIYTKLIKFTSWIKE 249

Fly 255 254
Rat 250 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	88/235 (37%)
CG8299	NP_611066.1	Tryp_SPc	28..255	CDD:238113	91/238 (38%)
Klk1c3	NP_001258244.1	Tryp_SPc	24..247	CDD:214473	88/235 (37%)
Klk1c3	NP_001258244.1	Tryp_SPc	25..250	CDD:238113	91/238 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920