DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8299 and Klk11

DIOPT Version :9

Sequence 1:	NP_611066.1	Gene:	CG8299 / 36751	FlyBaseID:	FBgn0034052	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001099722.1	Gene:	Klk11 / 292849	RGDID:	1308690	Length:	279	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	85/260 - (32%)
Similarity:	132/260 - (50%)	Gaps:	17/260 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLRLGLFLLAALGVVILTDSASISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVV 66
            :|...:.:|..:.:.::|......|.|:.|.:......|:||::..:|.:|   ||.::.||:.:
  Rat    25 ALLQAMMILRFIALALVTGHVGGETRIIKGYECRPHSQPWQVALFQKTRLL---CGATLIAPKWL 86

  Fly    67 ITAAHCIKGRYASYIRIVAGQNSIADLE--EQGVKVSKLIPHAGYN----KKTYVNDIGLIITRE 125
            :|||||.|..|.    |:.|::::...:  ||....::..||.|:|    .|.:.|||.|:....
  Rat    87 LTAAHCRKPHYV----ILLGEHNLEKTDGCEQRRMATESFPHPGFNNSLPNKDHRNDIMLVKMSS 147

  Fly   126 PLEYSALVQPIAVALEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDY 190
            |...:..|:|:.::.....:|...::||||..:.....||..||...:.||....|...|   ..
  Rat   148 PAFITRAVRPLTLSSLCVTAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIGHKECERAY---PG 209

  Fly   191 TVTDEMLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWGVG-CGREGFPGVYTSVNSHIDWIEE 254
            .:||.||||...:.|||:|.|||||||..:|.|.|::|||.. |.....|||||.|..:.|||.|
  Rat   210 NITDTMLCASVRKEGKDSCQGDSGGPLVCNGSLQGIISWGQDPCAVTRKPGVYTKVCKYFDWIHE 274

Fly 255 254
Rat 275 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	78/231 (34%)
CG8299	NP_611066.1	Tryp_SPc	28..255	CDD:238113	81/234 (35%)
Klk11	NP_001099722.1	Tryp_SPc	50..272	CDD:214473	78/231 (34%)
Klk11	NP_001099722.1	Tryp_SPc	51..275	CDD:238113	81/234 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920