Protein Alignment CG8299 and PRSS33

DIOPT Version :10

• Sequence 1: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 99/276 - (35%)
• Similarity: 136/276 - (49%)
• Gaps: 34/276 - (12%)

  Fly     5 LGLFLLAALGVVILTDSAS-------ISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYA 62
            |.:.||..||........|       :|:.||||......::|:|.|::   :...|:||||:.|
Human     7 LQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQ---HRGAHVCGGSLIA 68

  Fly    63 PRVVITAAHCIKGRY--ASY-IRIVA---GQNSIADLEEQGVKVSKLIPHAGYNKKTYVNDIGLI 121
            |:.|:|||||...|.  |.| :|:.|   |..|...|   .|.|.:::....|::.....|:.|:
Human    69 PQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTL---SVPVRRVLLPPDYSEDGARGDLALL 130

  Fly   122 ITREPLEYSALVQPIAVALEA--PPSGAQAVVSGWGKRAEDDEALPAM--LRAVELQIIEKSTC- 181
            ..|.|:..||.|||:.:.:..  ||.|....|:|||. ......||..  |:.|.:.:::..||
Human   131 QLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGS-LRPGVPLPEWRPLQGVRVPLLDSRTCD 194

  Fly   182 -----GAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAV----DGVLVGVVSWGVGCGREG 237
                 ||.....:..|....|||||.:|.||.|.|||||||..    ..|||||||||.||....
Human   195 GLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPN 259

  Fly   238 FPGVYTSVNSHIDWIE 253
            .|||||||.::..||:
Human   260 RPGVYTSVATYSPWIQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	90/244 (37%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	91/244 (37%)