Protein Alignment CG8299 and KLK5

DIOPT Version :9

• Sequence 1: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001070959.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 79/238 - (33%)
• Similarity: 124/238 - (52%)
• Gaps: 14/238 - (5%)

  Fly    25 STHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIVAGQNS 89
            |:.|:.|...|:...|:|.::.|....|  .||..:..|:.::|||||.|    ...|:..|..|
Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQL--YCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYS 122

  Fly    90 IADLEEQGVKV---SKLIPHAGYNKKTYVNDIGLIITREPLEYSALVQPIAVALEAPPSGAQAVV 151
            ::.:.|.|.::   .|.|||.||:...:.||:.||.....:..:..|:||.|:...|.:|.:.:|
Human   123 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLV 187

  Fly   152 SGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGP 216
            ||||.........|.:|:.:.:.::.:..|...|..:   :.|.|.|||. :.|:|:|.||||||
Human   188 SGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ---IDDTMFCAGD-KAGRDSCQGDSGGP 248

  Fly   217 LAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEEQAEA 258
            :..:|.|.|:|||| ..|.|...|||||::.....||:|..:|
Human   249 VVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	74/228 (32%)
		Tryp_SPc	28..255	CDD:238113	76/230 (33%)
KLK5	NP_001070959.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/3 (33%)
		Tryp_SPc	66..285	CDD:214473	74/228 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41500
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910