| Sequence 1: | NP_477127.1 | Gene: | Diap2 / 36748 | FlyBaseID: | FBgn0015247 | Length: | 498 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001186067.1 | Gene: | NLRC4 / 58484 | HGNCID: | 16412 | Length: | 1024 | Species: | Homo sapiens |
| Alignment Length: | 444 | Identity: | 80/444 - (18%) |
|---|---|---|---|
| Similarity: | 135/444 - (30%) | Gaps: | 160/444 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 73 CSMVLAPNHCGNVPRSQESDN--EGNSVVDSPESCSCPDLLLEANRLVTFKDWPNPNITPQALAK 135
Fly 136 AGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQP 200
Fly 201 TTLPLR---------PKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGL 256
Fly 257 RSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAPTLQAD------- 314
Fly 315 -------------------------------VLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGC 348
Fly 349 AFSTLDELLHDIFDDAGAGAALEVREPPEPSAPFIEPCQATTSKAASVPIPVADSIPAKPQAAEA 413
Fly 414 VANISKITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCG 467 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Diap2 | NP_477127.1 | BIR | 12..78 | CDD:237989 | 1/4 (25%) |
| BIR | 112..181 | CDD:197595 | 13/68 (19%) | ||
| BIR | 213..281 | CDD:237989 | 12/67 (18%) | ||
| UBA_IAPs | 320..363 | CDD:270506 | 9/42 (21%) | ||
| zf-C3HC4_3 | 447..492 | CDD:290631 | 4/21 (19%) | ||
| NLRC4 | NP_001186067.1 | CARD | 1..87 | CDD:279013 | |
| Nucleotide-binding domain (NBD). /evidence=ECO:0000250 | 95..298 | ||||
| NACHT | 163..316 | CDD:283404 | |||
| Winged-helix domain (WHD). /evidence=ECO:0000250 | 356..463 | ||||
| LRR 1 | 578..598 | 6/26 (23%) | |||
| LRR 2 | 656..679 | 4/32 (13%) | |||
| leucine-rich repeat | 691..713 | CDD:275381 | 6/40 (15%) | ||
| LRR 3 | 735..758 | 0/22 (0%) | |||
| LRR_RI | 738..978 | CDD:238064 | 31/183 (17%) | ||
| leucine-rich repeat | 738..764 | CDD:275380 | 0/25 (0%) | ||
| LRR 4 | 762..785 | 4/22 (18%) | |||
| leucine-rich repeat | 765..789 | CDD:275380 | 5/30 (17%) | ||
| LRR 5 | 787..812 | 9/37 (24%) | |||
| leucine-rich repeat | 790..817 | CDD:275380 | 9/32 (28%) | ||
| leucine-rich repeat | 822..849 | CDD:275380 | 4/37 (11%) | ||
| LRR 6 | 824..847 | 4/33 (12%) | |||
| LRR 7 | 848..870 | 5/22 (23%) | |||
| leucine-rich repeat | 850..880 | CDD:275380 | 4/30 (13%) | ||
| LRR 8 | 878..902 | 4/12 (33%) | |||
| leucine-rich repeat | 881..908 | CDD:275380 | 3/9 (33%) | ||
| leucine-rich repeat | 909..938 | CDD:275380 | |||
| LRR 9 | 911..933 | ||||
| LRR 10 | 936..963 | ||||
| leucine-rich repeat | 939..966 | CDD:275380 | |||
| LRR 11 | 965..985 | ||||
| LRR 12 | 999..1021 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165140727 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.930 | |||||