DRSC/TRiP Functional Genomics Resources

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Protein Alignment Diap2 and Mylip

DIOPT Version :10

Sequence 1:NP_477127.1 Gene:Diap2 / 36748 FlyBaseID:FBgn0015247 Length:498 Species:Drosophila melanogaster
Sequence 2:NP_001100814.2 Gene:Mylip / 306825 RGDID:1305761 Length:445 Species:Rattus norvegicus


Alignment Length:104 Identity:34/104 - (32%)
Similarity:53/104 - (50%) Gaps:11/104 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   400 VADSIPAKPQAAEAVANISKITDEIQKMSVATPNGNLS------LEEENRQLKDARLCKVCLDEE 458
            |.|.:....|:..:    |.:......||.::..| ||      |:|:.|:||:|.||.||.:||
  Rat   335 VVDLVSRNDQSPPS----SPLKSSDSSMSCSSCEG-LSCQQTRVLQEKLRKLKEAMLCMVCCEEE 394

  Fly   459 VGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFL 497
            :...|.||||...|..||..:.:||:||:.::.....:|
  Rat   395 INSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVYL 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Diap2NP_477127.1 BIR 12..78 CDD:237989
BIR 112..181 CDD:197595
BIR 213..281 CDD:237989
UBA_IAPs 320..363 CDD:270506
RING-HC_BIRC2_3_7 442..498 CDD:438373 23/56 (41%)
MylipNP_001100814.2 FERM_F1_MYLIP 1..81 CDD:340624
B41 5..190 CDD:214604
FERM_C_MYLIP_IDOL 185..295 CDD:270016
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 341..363 4/25 (16%)
RING-HC_MYLIP 383..434 CDD:438186 20/51 (39%)
Critical for homodimerization. /evidence=ECO:0000250 431..433 0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

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