DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Diap2 and Mylip

DIOPT Version :9

Sequence 1:	NP_477127.1	Gene:	Diap2 / 36748	FlyBaseID:	FBgn0015247	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001100814.2	Gene:	Mylip / 306825	RGDID:	1305761	Length:	445	Species:	Rattus norvegicus

Alignment Length:	104	Identity:	34/104 - (32%)
Similarity:	53/104 - (50%)	Gaps:	11/104 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 VADSIPAKPQAAEAVANISKITDEIQKMSVATPNGNLS------LEEENRQLKDARLCKVCLDEE 458
            |.|.:....|:..:    |.:......||.::..| ||      |:|:.|:||:|.||.||.:||
  Rat   335 VVDLVSRNDQSPPS----SPLKSSDSSMSCSSCEG-LSCQQTRVLQEKLRKLKEAMLCMVCCEEE 394

  Fly   459 VGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFL 497
            :...|.||||...|..||..:.:||:||:.::.....:|
  Rat   395 INSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVYL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Diap2	NP_477127.1	BIR	12..78	CDD:237989
		BIR	112..181	CDD:197595
		BIR	213..281	CDD:237989
		UBA_IAPs	320..363	CDD:270506
		zf-C3HC4_3	447..492	CDD:290631	19/44 (43%)
Mylip	NP_001100814.2	FERM_F1_MYLIP	1..81	CDD:340624
		B41	5..190	CDD:214604
		FERM_C_MYLIP_IDOL	185..295	CDD:270016
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	341..363		4/25 (16%)
		RING-HC_MYLIP	386..423	CDD:319437	17/36 (47%)
		Critical for homodimerization. /evidence=ECO:0000250	431..433		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340284at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010