Protein Alignment Diap2 and Naip6

DIOPT Version :9

• Sequence 1: NP_477127.1
• Gene: Diap2 / 36748
• FlyBaseID: FBgn0015247
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_035001.2
• Gene: Naip6 / 17952
• MGIID: 1298222
• Length: 1403
• Species: Mus musculus
• Alignment Length: 465
• Identity: 119/465 - (25%)
• Similarity: 188/465 - (40%)
• Gaps: 106/465 - (22%)

  Fly     6 MELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQV----AERH 66
            |..|:.||.||..:......:.:::.|.||:.||..|..:|..|.:.:    :|:.:    .|||
Mouse    57 MRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIERH 117

  Fly    67 RRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCPDLLL---------EANRLVTFKD 122
            ::..|.|.. |.....||:       .:.:..|.|||.      :|         |..||.:|:|
Mouse   118 KKLRPECEF-LQGKDVGNI-------GKYDIRVKSPEK------MLRGGKARYHEEEARLESFED 168

  Fly   123 WP--NPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLI 185
            ||  ....:|:||:.|||.:..:.|.|:|..|.|.:..||:.|:.::||.::||:|..:|.....
Mouse   169 WPFYAHGTSPRALSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSS 233

  Fly   186 E-------------FATGKNLDELGIQPTTLPLRPKYACVDA-------RLRTFTDWPISNIQPA 230
            |             ..||::..:..:: ..||:...| |.|:       |:..|.|||..:....
Mouse   234 EEIAQYIQDYEGFVHVTGEHFVKSWVR-RELPMVSAY-CNDSVFTNEELRMDMFKDWPQESPVGF 296

  Fly   231 SALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATT 295
            .||.:||.:|....|.||||.|...|..|.:.|:|..:|.|:.|:|.|:...|..|   ||:
Mouse   297 EALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSA---EVI--- 355

  Fly   296 AANASSQPATAPAPTLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFS---TLDELL 357
                         ||||:...:.||......:...|...|.:.:.....|....|.   :|.|.|
Mouse   356 -------------PTLQSQYALPEATETTRESNHDDAAAVHSTVVDLGRSEAQWFQEARSLSEQL 407

  Fly   358 HDIFDDAGAGAALEVREPPEPSAPFIEPCQ------------ATTSKAASVPIPVADSIPAKPQA 410
            .|.:...   :...:..|        |.|.            :..||..|.|:..|.:||
Mouse   408 RDTYTKT---SFCHMNLP--------EVCSSLGTDHLLGCDVSIISKHVSQPVQGALTIP----- 456

  Fly   411 AEAVANISKI 420
             |..:|:|.:
Mouse   457 -EVFSNLSSV 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Diap2	NP_477127.1	BIR	12..78	CDD:237989	18/69 (26%)
		BIR	112..181	CDD:197595	27/79 (34%)
		BIR	213..281	CDD:237989	26/74 (35%)
		UBA_IAPs	320..363	CDD:270506	9/45 (20%)
		zf-C3HC4_3	447..492	CDD:290631
Naip6	NP_035001.2	BIR 1	60..127		19/71 (27%)
		BIR	61..129	CDD:237989	19/72 (26%)
		BIR 2	159..227		26/67 (39%)
		BIR	162..228	CDD:279047	25/65 (38%)
		BIR	277..346	CDD:197595	25/68 (37%)
		BIR 3	278..345		24/66 (36%)
		NACHT	464..618	CDD:283404	0/2 (0%)
		AMN1	1072..1271	CDD:187754
		leucine-rich repeat	1132..1156	CDD:275381
		leucine-rich repeat	1157..1182	CDD:275381
		leucine-rich repeat	1183..1207	CDD:275381
		leucine-rich repeat	1208..1233	CDD:275381
		leucine-rich repeat	1234..1264	CDD:275381
		leucine-rich repeat	1265..1293	CDD:275381
		leucine-rich repeat	1294..1322	CDD:275381

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830702
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840