DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bdg and ZDS1

DIOPT Version :9

Sequence 1:	NP_611064.2	Gene:	bdg / 36747	FlyBaseID:	FBgn0034049	Length:	1331	Species:	Drosophila melanogaster
Sequence 2:	NP_014000.1	Gene:	ZDS1 / 855316	SGDID:	S000004886	Length:	915	Species:	Saccharomyces cerevisiae

Alignment Length:	565	Identity:	108/565 - (19%)
Similarity:	185/565 - (32%)	Gaps:	190/565 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SSLPPTGTGAGCSGAALGSGTGTGKRARSKQHQLEHEQFGLSNSLSSESIRQACAYYDDELSDED 85
            |::|...|......::|........|.||::.:.|.||          |:        ||:.::|
Yeast   347 SNMPINNTMTWPERSSLRRSRFNTYRIRSQEQEKEVEQ----------SV--------DEMKNDD 393

  Fly    86 -----------LIEIQQTPQAFHQQTKQPLQL-QPISFRLGD-----------------ELGDER 121
                       .:||......|.||.:....: .|.|  :||                 |:|.|:
Yeast   394 EERLKLTKNTIKVEIDPHKSPFRQQDEDSENMSSPGS--IGDFQDIYNHYRQSSGEWEQEMGIEK 456

  Fly   122 SAFCGSQEMQQVPLSTPIKQAAETDEALCVLSELDAILDVHDVSQLNGTCSSGSVNSGSDDDKVE 186
                   |.::|    |:|...:|.|              .|:....||  :..|...:.||..|
Yeast   457 -------EAEEV----PVKVRNDTVE--------------QDLELREGT--TDMVKPSATDDNKE 494

  Fly   187 DYLMDLDNYLEEMDNALNREDSLIIIDGHTSLKREPRTRTLPLSRKKK--------------SSK 237
            .......|....::|.::|||......|....:....::.:.|...||              |:|
Yeast   495 TKRHRRRNGWTWLNNKMSREDDNEENQGDDENEENVDSQRMELDNSKKHYISLFNGGEKTEVSNK 559

  Fly   238 KKSEDQEAAQGDFQREHQLRKTFSCSLRPT---SQIASSSGSLETSTEPVMD----VWRRQSMRR 295
            ::..:...:....|...::.|||:...|..   ...||||.|...|:.|.:.    |..|....:
Yeast   560 EEMNNSSTSTATSQTRQKIEKTFANLFRRKPHHKHDASSSPSSSPSSSPSIPNNDAVHVRVRKSK 624

  Fly   296 ALEQEDTKATVAMEREEDDIPTLLVELP-PRRDAEMRRCFSQGDCQASVAPTVGSQMLTEAHIFD 359
            .|..:..:..|.        |.:|...| |.|....|.               |||.::...:.|
Yeast   625 KLGNKSGREPVE--------PIVLRNRPRPHRHHHSRH---------------GSQKISVKTLKD 666

  Fly   360 NLLQTNARASSEEPRPRQYGRRLEGPPTPVRPLIL------------AQSRPQSAP------TRV 406
            :             :|:|        ..|::|.:.            ::|.||..|      |:.
Yeast   667 S-------------QPQQ--------QIPLQPQLEGAIEIEKKEESDSESLPQLQPAVSVSSTKS 710

  Fly   407 QMREPQLQDT-PTHPIMSTCSELSSARSSR-------------MPSP------VSLPSDSSSSGS 451
            ..|:.:.::. ..:...|..:|:|:.:.|:             :.:|      .|:|..:|:...
Yeast   711 NSRDREEEEAKKKNKKRSNTTEISNQQHSKHVQKENTDEQKAQLQAPAQEQVQTSVPVQASAPVQ 775

  Fly   452 SSAEHDQEPDPVQTTTMCSASSTT---PLEPLHQLQLLLREKCGF 493
            :||       ||||:....||:.|   ...||....:|...|..|
Yeast   776 NSA-------PVQTSAPVEASAQTQAPAAPPLKHTSILPPRKLTF 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356
ZDS1	NP_014000.1	tatB	<732..809	CDD:166942	19/83 (23%)
ZDS1	NP_014000.1	Zds_C	845..893	CDD:370018
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950