Protein Alignment bdg and Slc6a2

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 157/688 - (22%)
• Similarity: 270/688 - (39%)
• Gaps: 142/688 - (20%)

  Fly   457 DQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQ----WPHAGSRTLALIGCTLGVFNM 517
            ||.|:  |....|..:....::..:.:|.||..:.| ::|    |.......|:::|..:.:.|:
  Rat    18 DQLPE--QPLRPCKTADLLVVKEHNGVQCLLASQDG-DAQPRETWGKKIDFLLSVVGFAVDLANV 79

  Fly   518 CRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMWKISPICAGVGIALVMQ 581
            .||..|.. |.||.||:.:.|..:|.|:||.::::.||...|.|..::|||.|...|||.|:::.
  Rat    80 WRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILI 144

  Fly   582 QCFLALYSTVSLAWILVYLRDVFPTA---ARSGYRWQ--EMAFPYRYDASNATGNLTQ------- 634
            ..::..|..|.:||.|.||...|...   ...|:.|.  ....|...:|| ..|:.|:
  Rat   145 ALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNAS-VLGDHTKYSKYKFT 208

  Fly   635 TVAEYFNVVVLQRLHLANHPDASGIR-FHVNDRQLAFYLALIWAAVFLILCKGLKSLGKLAYIIY 698
            ..||::...|| .||     ::|||. ..:...||...|.::...::..|.||:|:.||:.:|..
  Rat   209 PAAEFYERGVL-HLH-----ESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITA 267

  Fly   699 TLPLVALAVVTAKFVYVVDPSRIQNIFAASDFDDFLVNSNSW-TAATQETFLTWGLLGASVIAIT 762
            |||...|.|:....|.:...|...|.:...||.. |..:..| .||||
  Rat   268 TLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYR-LKEATVWIDAATQ----------------- 314

  Fly   763 SRSHTNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSL 827
                                :|..:|.|...|:|..        .|    ..|:| :||..  :|
  Rat   315 --------------------IFFSLGAGFGVLIAFA--------SY----NKFDN-NCYRD--AL 344

  Fly   828 QSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVES-GFQALRFISEIFPAVLSLASDSISWV 891
            .::|    ::...|.|..::.|....|..:...:.:|. ..:....:..::|..:|..|.|.  .
  Rat   345 LTST----INCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGST--F 403

  Fly   892 WAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSV---------------LLSCVTGL---LLSI 938
            ||.:.|......||          .|::|...:.:               |.:|...|   ||::
  Rat   404 WAVLFFLMLLALGL----------DSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAM 458

  Fly   939 PFATEMGISILYYVD-FLLGGSWFIPIIWTAQIFGVFLIRGRPYNGDDLVNDL-RLCG-SMSAFL 1000
            ...|:.||.:|..:| |..|.|....::..|  .||...    |..|...||: ::.| ....:.
  Rat   459 FCITKGGIYVLTLLDTFAAGTSILFAVLMEA--IGVSWF----YGVDRFSNDIQQMMGFKPGLYW 517

  Fly  1001 ALSWNVLLP---IGLITLSVVDYKASLSNQFYYWRGKSYFTYWSRKMGSLIQIGVLLVIPVTAII 1062
            .|.|..:.|   :.::.:|::::|....:.:.|       ..|:..:|..|.:..::::|...
  Rat   518 RLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVY-------PPWANWVGWGIALSSMILVPAYV-- 573

  Fly  1063 QIYRYLA-HGPPDILERIQLLYRPPEEGEEPRRPSARQ 1099
             ||::.: .|  .:.||:.....|..|.....:...||
  Rat   574 -IYKFFSIRG--SLWERVAYGITPENEHHLVAQRDVRQ 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	122/509 (24%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:444915	147/647 (23%)