Protein Alignment bdg and Slc6a19

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_083154.1
• Gene: Slc6a19 / 74338
• MGIID: 1921588
• Length: 634
• Species: Mus musculus
• Alignment Length: 619
• Identity: 129/619 - (20%)
• Similarity: 247/619 - (39%)
• Gaps: 140/619 - (22%)

  Fly   480 LHQLQLLLREKCGFNSQWPHAGSRTLALIGCTLGVFNMCRFAVLTINFGGN-FLLQFLLLSVIFG 543
            |.:|:::.:|:.|...:|.:.....|..:|..:|:.|:.||..|..:.||. |::.||:|.|..|
Mouse    18 LDELEVIEKEEAGSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEG 82

  Fly   544 IPLLWLQMCLGAKIRAGPVSMW-KISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTA 607
            ||||:|:..:|.::|.|.:.:| .|.|...|:|||.:.....:.||....:||::.|..:.|
Mouse    83 IPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSF--- 144

  Fly   608 ARSGYRWQEMAFPYRYDASNATGNLTQ----TVAEYFNVVVLQRLHLANH-PDASGIRFHVNDRQ 667
             :....|.|...     ..|.||.:.:    :..:||  ...:.|:::.. .|:..|::.:
Mouse   145 -QEPLPWSECPL-----NQNQTGYVEECAKSSSVDYF--WYRETLNISTSISDSGSIQWWI---- 197

  Fly   668 LAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAV----------VTAKFVYVVDPSRIQ 722
             ...|...|:.:::.:.:|:::.||..||..|||.|.|.:          .|...|::..|:..:
Mouse   198 -LLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITE 261

  Fly   723 NIFAASDFDDFLVNSNSWTAATQETFLTWGLLGASVIAITSRSHTNANKAALRRDAILL------ 781
                       |.|.|:|..|..:.|.::.|....:|:.:|.:..:.|   ...|::::
Mouse   262 -----------LSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNN---CEMDSVIVSVINGF 312

  Fly   782 -------VLFTLIGL------------GLMALLALCCAQILWQHGYVYVPGSF--ENPDCYTSIY 825
                   |::::||.            .::.|:          :|:....|:.  ||.:.|....
Mouse   313 TSVYAATVVYSIIGFRATERFDDCVNTNILTLI----------NGFDLPEGNVTSENFEAYQQWC 367

  Fly   826 SLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRFISEIFPAVLSLASDSISW 890
            :.   |||...:..:......:||:.|         .||.  ..|.||  :|..  ::....:|.
Mouse   368 NA---TNPQAYAQLKFQTCDINSFLSE---------GVEG--TGLAFI--VFTE--AITKMPVSP 414

  Fly   891 VWAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSVL-------------------LSCVTGLLL 936
            :|:.:.|......||          ||..||....|:                   |.|:...|:
Mouse   415 LWSVLFFIMLFCLGL----------SSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLI 469

  Fly   937 SIPFATEMGISILYYVDFLLGGSWFIPIIWTA--QIFGVFLIRGRPYNGDDLVNDLRLCGSMSAF 999
            :..|....|...|..:|...|.   ||::..|  ::|.|..:.|......|:  :..:....:.|
Mouse   470 AFIFTLNSGQYWLSLLDSFAGS---IPLLIIAFCEMFAVVYVYGVDRFNKDI--EFMIGHKPNIF 529

  Fly  1000 LALSWNVLLPIGLITLSVVDYKASLSNQFYY--W 1031
            ..::|.|:.|:.::.:.:..:...::....|  |
Mouse   530 WQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIW 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	116/539 (22%)
Slc6a19	NP_083154.1	SLC5-6-like_sbd	32..612	CDD:444915	125/605 (21%)