Protein Alignment bdg and SLC6A13

DIOPT Version :9

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 705
• Identity: 174/705 - (24%)
• Similarity: 267/705 - (37%)
• Gaps: 157/705 - (22%)

  Fly   463 VQTTTMCSASSTTPLEPLHQLQLLLREKCGF--NSQWPHAGSRTLALIGCTLGVFNMCRFAVLTI 525
            |..||  |...|.|:.|:.:    .:|:.|.  ...|.:.....|::.|..:|:.|:.||..|..
Human     5 VSGTT--SNGETKPVYPVME----KKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCY 63

  Fly   526 -NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMW-KISPICAGVGIALVMQQCFLALY 588
             |.||.|.:.:|:.....|||:..|:..||.....|.|:.| ||.||..|:|.|..|....|.:|
Human    64 KNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVY 128

  Fly   589 STVSLAWILVYLRDVFPTAARSG---YRWQE---MAFPYRYDASNATG-NLTQTVAEYFNVVVLQ 646
            ..:.|||.|.||...|......|   :.|..   |.|.....:.|.|. |.|..|.|::...||:
Human   129 YIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERRVLK 193

  Fly   647 RLHLANHPDASGIRFHVNDRQLAFYLALIWAAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAK 711
            ......|..|  :|:     :||..|.|.|...:..:.||:||.||:.|...|.|.:.|.|:..:
Human   194 ISDGIQHLGA--LRW-----ELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIR 251

  Fly   712 FVYVVDPSRIQNIFAASDFDDFLVNSN--------SWTAATQETFLTWGLLGASVIAITS--RSH 766
            .|.:  |...|.|       .|.:..|        .|..|..:.|.::.:....:.|:.|  :.|
Human   252 GVTL--PGAAQGI-------QFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYH 307

  Fly   767 TNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSLQSNT 831
            .|.     .||.|                |||    ....|..:|.|        .:|:|:..
Human   308 NNC-----YRDCI----------------ALC----FLNSGTSFVAG--------FAIFSILG-- 337

  Fly   832 NPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRFISEIFP-AVLSLASDSISWVWAAV 895
               .:|..:. :|     |.|.         .||| ..|.||:  :| ||:.|   ..|.:||..
Human   338 ---FMSQEQG-VP-----ISEV---------AESG-PGLAFIA--YPRAVVML---PFSPLWACC 378

  Fly   896 AFATFAGFGLAQLCVMWKPISSAL----------GNSTSSVLLS-CVTGLLLSIPFATEMGISIL 949
            .|......||....|..:.:.:||          .|....::|. .|...|:.:...||.|:.:.
Human   379 FFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVF 443

  Fly   950 YYVDFLLGGSW---FIPI---IWTAQIFGVFLIRGRPY-NGDDLVND-----LRLCGSMSAFLAL 1002
            ...|:......   |:.|   :..|.::|.    .|.| |.:|::..     ::.|
Human   444 QLFDYYAASGMCLLFVAIFESLCVAWVYGA----KRFYDNIEDMIGYRPWPLIKYC--------- 495

  Fly  1003 SWNVLLP---IGLITLSVVDYKASLSNQFYYWRGKSYFTYWSRKMGSLIQIGVLLVIPVTAIIQI 1064
             |..|.|   ......|::.|.....|:.|      .:.:|...:|.|:.:..::.||..:   :
Human   496 -WLFLTPAVCTATFLFSLIKYTPLTYNKKY------TYPWWGDALGWLLALSSMVCIPAWS---L 550

  Fly  1065 YRY-LAHGPPDILERIQLLYRPPEEGEEPRRPSARQTASQSRRNALGQTTEGGQH 1118
            ||. ...||  ..|||:.|..|.|  :.|:|..|..:|..:.|.:|.:.||...|
Human   551 YRLGTLKGP--FRERIRQLMCPAE--DLPQRNPAGPSAPATPRTSLLRLTELESH 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	128/511 (25%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		7/18 (39%)
		SLC6sbd_GAT2	32..575	CDD:271396	156/644 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900