Protein Alignment bdg and SLC6A11

DIOPT Version :10

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Alignment Length: 711
• Identity: 159/711 - (22%)
• Similarity: 266/711 - (37%)
• Gaps: 171/711 - (24%)

  Fly   431 ARSSRMPSPVSLPSDSSSSGSSSAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGF-N 494
            ||.|..|.     ...||.|::.|.|.:                           :.|:|... .
Human    18 ARESEAPG-----GGCSSGGAAPARHPR---------------------------VKRDKAVHER 50

  Fly   495 SQWPHAGSRTLALIGCTLGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIR 558
            ..|.:.....|::.|..:|:.|:.||..|.. |.||.||:.:::..:..|||:.:|:..||....
Human    51 GHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTS 115

  Fly   559 AGPVSMW-KISPICAGVGIALVMQQCFLALYSTVSLAWILVYLRDVFPTA---ARSGYRWQ-EMA 618
            .|.::.| |:.|:..|:|.|..:.:..|.:|..:.|||.:.||.:.|.|.   |..|:.|. |..
Human   116 EGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC 180

  Fly   619 FPY-RYDASN----ATGNLTQTVAEYFNVVVLQRLHLANHPDASGIRFHVNDR-QLAFYLALIWA 677
            ..: :.:.||    :..|.|..|.|::...||        ..:.||....|.| :||..|...|.
Human   181 VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVL--------AISDGIEHIGNLRWELALCLLAAWT 237

  Fly   678 AVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAKFVYVVDPSRIQNIFAASDFDDFLVNSNSWTA 742
            ..:..:.||.||.||:.|:..|.|.:.|.::..:.|.:...|.....:...|... |.:...|..
Human   238 ICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSR-LSDPQVWVD 301

  Fly   743 ATQETFLTWGLLGASVIAITSRSHTNANKAALRRDAILLVLFTLIGLGLMALLALCCAQILWQHG 807
            |..:.|.::.:....:.|:.|.::.|.|   ..||.|:                |||.    ..|
Human   302 AGTQIFFSYAICLGCLTALGSYNNYNNN---CYRDCIM----------------LCCL----NSG 343

  Fly   808 YVYVPGSFENPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRNRTMIHVESGFQALRF 872
            ..:|.|        .:|:|:..     .::|.:. :|     |.|.         .||| ..|.|
Human   344 TSFVAG--------FAIFSVLG-----FMAYEQG-VP-----IAEV---------AESG-PGLAF 379

  Fly   873 ISEIFPAVLSLASDSISWVWAAVAFATFAGFGLAQLCVMWKPISSALGNSTSSV----------- 926
            |:  :|..:::.  .:|.:||.:.|......||....|..:.:.:|:.:....|
Human   380 IA--YPKAVTMM--PLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLI 440

  Fly   927 LLSCVTGLLLSIPFATEMGISILYYVDFLLGGSW---FIPI---IWTAQIFGVFLIRGRPY-NGD 984
            |...|....|.:...||.|:.|....|.......   |:.|   |....::|    ..|.| |.:
Human   441 LALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYG----SNRFYDNIE 501

  Fly   985 DLV-----NDLRLCGSMSAFLALSWNVLLP---IGLITLSVVDYKASLSNQFYYWRGKSYFTY-- 1039
            |::     :.::.|          |.::.|   .|:....::.||....|..|        ||
Human   502 DMIGYRPPSLIKWC----------WMIMTPGICAGIFIFFLIKYKPLKYNNIY--------TYPA 548

  Fly  1040 WSRKMGSLIQIGVLLVIPVTAIIQIYRYLAHGPPDILERIQLLYRPPEE-------GEEPR 1093
            |...:|.|:.:..:|.||:...|.:::.....|    |::|.|..|..:       |..||
Human   549 WGYGIGWLMALSSMLCIPLWICITVWKTEGTLP----EKLQKLTTPSTDLKMRGKLGVSPR 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	118/503 (23%)
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		9/54 (17%)
		SLC6sbd_GAT3	49..590	CDD:212077	144/631 (23%)