Protein Alignment bdg and SLC6A9

DIOPT Version :9

• Sequence 1: NP_611064.2
• Gene: bdg / 36747
• FlyBaseID: FBgn0034049
• Length: 1331
• Species: Drosophila melanogaster
• Sequence 2: NP_964012.2
• Gene: SLC6A9 / 6536
• HGNCID: 11056
• Length: 706
• Species: Homo sapiens
• Alignment Length: 797
• Identity: 171/797 - (21%)
• Similarity: 289/797 - (36%)
• Gaps: 214/797 - (26%)

  Fly   404 TRVQMREPQLQD-----TPTHPIMSTCSELSSARSSRMPSPVSLPSDSSSSGSS----------- 452
            ||..:..|::..     .|:.|...|.  |...||..:| |.|..:.|:|...|
Human     6 TRAAIARPRMAAAHGPVAPSSPEQVTL--LPVQRSFFLP-PFSGATPSTSLAESVLKVWHGAYNS 67

  Fly   453 ------SAEHDQEPDPVQTTTMCSASSTTPLEPLHQLQLLLREKCGFNSQWPHAGSRTLALIGCT 511
                  .|:|         :...:.:...|.|...:.|.|.|      ..|.:.....|..:|..
Human    68 GLLPQLMAQH---------SLAMAQNGAVPSEATKRDQNLKR------GNWGNQIEFVLTSVGYA 117

  Fly   512 LGVFNMCRFAVLTI-NFGGNFLLQFLLLSVIFGIPLLWLQMCLGAKIRAGPVSMWKISPICAGVG 575
            :|:.|:.||..|.. |.||.|:..:.::.:..||||.::::..|.....|.:.:|:|||:..|||
Human   118 VGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVG 182

  Fly   576 IALVMQQCFLALYSTVSLAWILVY----LRDVFPTAARSGYRWQEMAFPYR-------YDASNAT 629
            ..:::...::.:|..|.:.....|    :..|.|        |.....|:.       .||||.|
Human   183 YGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLP--------WAYCNNPWNTHDCAGVLDASNLT 239

  Fly   630 GNLTQTVAEYFNVVVLQRLHLANH------PDASGIRFHV----ND--------RQLAFYLALIW 676
             |.::..|...|:     .||.||      |.....|.:|    :|        ..|...|.:.|
Human   240 -NGSRPAALPSNL-----SHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSW 298

  Fly   677 AAVFLILCKGLKSLGKLAYIIYTLPLVALAVVTAK----------FVYVVDPSRIQNIFAASDFD 731
            ..|||.|.:|:||.||:.|...|.|.|.|.::..:          .:|.:.|..
Human   299 LVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQW----------- 352

  Fly   732 DFLVNSNSWTAATQETFLT----WGLLGASVIAITSRSHTNANKAALRRDAILLVLFTLIGLGLM 792
            |.::.:..|..|..:.|.:    ||  |...:|..::.|.|.     .||::::.:
Human   353 DKILEAKVWGDAASQIFYSLGCAWG--GLITMASYNKFHNNC-----YRDSVIISI--------- 401

  Fly   793 ALLALCCAQILWQHGYVYVPGSFENPDCYTSIYSLQSNTNPYLLSYPRSLIPHYSSFIGETYRRN 857
                                     .:|.||:|:      .:::.   |::...::.:|....|
Human   402 -------------------------TNCATSVYA------GFVIF---SILGFMANHLGVDVSR- 431

  Fly   858 RTMIHVESGFQALRFISEIFPAVLSLASDSISWVWAAVAFATFAGFGL-AQLCVMWKPISS---A 918
                 |......|.|::  :|..|:|.  .||.:|:.:.|......|| .|.|::...:::   .
Human   432 -----VADHGPGLAFVA--YPEALTLL--PISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDE 487

  Fly   919 LGN------STSSVLLSCVTGLLLSIPFATEMGISILYYVDFLLGGSWFIPIIWTAQIFGVFLIR 977
            :||      .|...|...|.|.||.||..::.||..|..:| ....|:.:.:|.......:..|.
Human   488 VGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMD-NYAASFSLVVISCIMCVAIMYIY 551

  Fly   978 GRPYNGDDLVNDLRLCGSMSAFLALSWNVLLP---IGLITLSVVDYKASLSNQFYYWRGKSYFTY 1039
            |......|:  .:.|......|..:.|..:.|   ..::..:|:.|:....|.:.|       ..
Human   552 GHRNYFQDI--QMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQY-------PG 607

  Fly  1040 WSRKMGSLIQIGVLLVIPVTAIIQIYR----------YLAHGP-----PDILERIQLLYRP---- 1085
            |:..:|.|:.:..:|.||:.|:.::.|          ..|..|     |.:||.....|.|
Human   608 WAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAP 672

  Fly  1086 -PEEGEE--PRRPSARQ 1099
             ||:|.|  |..|...|
Human   673 SPEDGFEVQPLHPDKAQ 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bdg	NP_611064.2	SLC5-6-like_sbd	501..976	CDD:271356	115/528 (22%)
SLC6A9	NP_964012.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		4/19 (21%)
		SLC6sbd_GlyT1	84..667	CDD:212067	145/683 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000